An efficient Volumetric Arc Therapy treatment planning approach for hippocampal-avoidance whole-brain radiation therapy (HA-WBRT)
Abstract
An efficient and simple class solution is proposed for hippocampal-avoidance whole-brain radiation therapy (HA-WBRT) planning using the Volumetric Arc Therapy (VMAT) delivery technique following the NRG Oncology protocol NRG-CC001 treatment planning guidelines. The whole-brain planning target volume (PTV) was subdivided into subplanning volumes that lie in plane and out of plane with the hippocampal-avoidance volume. To further improve VMAT treatment plans, a partial-field dual-arc technique was developed. Both the arcs were allowed to overlap on the in-plane subtarget volume, and in addition, one arc covered the superior out-of-plane sub-PTV, while the other covered the inferior out-of-plane subtarget volume. For all plans (n = 20), the NRG-CC001 protocol dose-volume criteria were met. Mean values of volumes for the hippocampus and the hippocampal-avoidance volume were 4.1 cm{sup 3} ± 1.0 cm{sup 3} and 28.52 cm{sup 3} ± 3.22 cm{sup 3}, respectively. For the PTV, the average values of D{sub 2%} and D{sub 98%} were 36.1 Gy ± 0.8 Gy and 26.2 Gy ± 0.6 Gy, respectively. The hippocampus D{sub 100%} mean value was 8.5 Gy ± 0.2 Gy and the maximum dose was 15.7 Gy ± 0.3 Gy. The corresponding plan quality indices were 0.30 ± 0.01 (homogeneity index), 0.94 ± 0.01more »
- Authors:
-
- Department of Radiation Oncology, Montefiore Medical Center and Albert Einstein College of Medicine, Bronx, NY (United States)
- Department of Medical Physics, University of Wisconsin, Madison, WI (United States)
- Publication Date:
- OSTI Identifier:
- 22462440
- Resource Type:
- Journal Article
- Journal Name:
- Medical Dosimetry
- Additional Journal Information:
- Journal Volume: 40; Journal Issue: 3; Other Information: Copyright (c) 2015 Elsevier Science B.V., Amsterdam, The Netherlands, All rights reserved.; Country of input: International Atomic Energy Agency (IAEA); Journal ID: ISSN 0958-3947
- Country of Publication:
- United States
- Language:
- English
- Subject:
- 61 RADIATION PROTECTION AND DOSIMETRY; AVOIDANCE; HIPPOCAMPUS; LIMITING VALUES; MONITORS; PLANNING; RADIATION DOSES; RADIOTHERAPY; RECOMMENDATIONS
Citation Formats
Shen, Jin, Bender, Edward, Yaparpalvi, Ravindra, Kuo, Hsiang-Chi, Basavatia, Amar, Hong, Linda, Bodner, William, Garg, Madhur K., Kalnicki, Shalom, Tomé, Wolfgang A., E-mail: wtome@montefiore.org, and Department of Medical Physics, University of Wisconsin, Madison, WI. An efficient Volumetric Arc Therapy treatment planning approach for hippocampal-avoidance whole-brain radiation therapy (HA-WBRT). United States: N. p., 2015.
Web. doi:10.1016/J.MEDDOS.2014.11.007.
Shen, Jin, Bender, Edward, Yaparpalvi, Ravindra, Kuo, Hsiang-Chi, Basavatia, Amar, Hong, Linda, Bodner, William, Garg, Madhur K., Kalnicki, Shalom, Tomé, Wolfgang A., E-mail: wtome@montefiore.org, & Department of Medical Physics, University of Wisconsin, Madison, WI. An efficient Volumetric Arc Therapy treatment planning approach for hippocampal-avoidance whole-brain radiation therapy (HA-WBRT). United States. https://doi.org/10.1016/J.MEDDOS.2014.11.007
Shen, Jin, Bender, Edward, Yaparpalvi, Ravindra, Kuo, Hsiang-Chi, Basavatia, Amar, Hong, Linda, Bodner, William, Garg, Madhur K., Kalnicki, Shalom, Tomé, Wolfgang A., E-mail: wtome@montefiore.org, and Department of Medical Physics, University of Wisconsin, Madison, WI. 2015.
"An efficient Volumetric Arc Therapy treatment planning approach for hippocampal-avoidance whole-brain radiation therapy (HA-WBRT)". United States. https://doi.org/10.1016/J.MEDDOS.2014.11.007.
@article{osti_22462440,
title = {An efficient Volumetric Arc Therapy treatment planning approach for hippocampal-avoidance whole-brain radiation therapy (HA-WBRT)},
author = {Shen, Jin and Bender, Edward and Yaparpalvi, Ravindra and Kuo, Hsiang-Chi and Basavatia, Amar and Hong, Linda and Bodner, William and Garg, Madhur K. and Kalnicki, Shalom and Tomé, Wolfgang A., E-mail: wtome@montefiore.org and Department of Medical Physics, University of Wisconsin, Madison, WI},
abstractNote = {An efficient and simple class solution is proposed for hippocampal-avoidance whole-brain radiation therapy (HA-WBRT) planning using the Volumetric Arc Therapy (VMAT) delivery technique following the NRG Oncology protocol NRG-CC001 treatment planning guidelines. The whole-brain planning target volume (PTV) was subdivided into subplanning volumes that lie in plane and out of plane with the hippocampal-avoidance volume. To further improve VMAT treatment plans, a partial-field dual-arc technique was developed. Both the arcs were allowed to overlap on the in-plane subtarget volume, and in addition, one arc covered the superior out-of-plane sub-PTV, while the other covered the inferior out-of-plane subtarget volume. For all plans (n = 20), the NRG-CC001 protocol dose-volume criteria were met. Mean values of volumes for the hippocampus and the hippocampal-avoidance volume were 4.1 cm{sup 3} ± 1.0 cm{sup 3} and 28.52 cm{sup 3} ± 3.22 cm{sup 3}, respectively. For the PTV, the average values of D{sub 2%} and D{sub 98%} were 36.1 Gy ± 0.8 Gy and 26.2 Gy ± 0.6 Gy, respectively. The hippocampus D{sub 100%} mean value was 8.5 Gy ± 0.2 Gy and the maximum dose was 15.7 Gy ± 0.3 Gy. The corresponding plan quality indices were 0.30 ± 0.01 (homogeneity index), 0.94 ± 0.01 (target conformality), and 0.75 ± 0.02 (confirmation number). The median total monitor unit (MU) per fraction was 806 MU (interquartile range [IQR]: 792 to 818 MU) and the average beam total delivery time was 121.2 seconds (IQR: 120.6 to 121.35 seconds). All plans passed the gamma evaluation using the 5-mm, 4% criteria, with γ > 1 of not more than 9.1% data points for all fields. An efficient and simple planning class solution for HA-WBRT using VMAT has been developed that allows all protocol constraints of NRG-CC001 to be met.},
doi = {10.1016/J.MEDDOS.2014.11.007},
url = {https://www.osti.gov/biblio/22462440},
journal = {Medical Dosimetry},
issn = {0958-3947},
number = 3,
volume = 40,
place = {United States},
year = {Thu Oct 01 00:00:00 EDT 2015},
month = {Thu Oct 01 00:00:00 EDT 2015}
}