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Title: Optimization of Radiation Therapy Techniques for Prostate Cancer With Prostate-Rectum Spacers: A Systematic Review

Dose-escalated radiation therapy for localized prostate cancer improves disease control but is also associated with worse rectal toxicity. A spacer placed between the prostate and rectum can be used to displace the anterior rectal wall outside of the high-dose radiation regions and potentially minimize radiation-induced rectal toxicity. This systematic review focuses on the published data regarding the different types of commercially available prostate-rectum spacers. Dosimetric results and preliminary clinical data using prostate-rectum spacers in patients with localized prostate cancer treated by curative radiation therapy are compared and discussed.
Authors:
 [1] ;  [2] ;  [2] ;  [1] ;  [3] ;  [1] ;  [1]
  1. Department of Radiation Oncology, Geneva University Hospital, Geneva (Switzerland)
  2. (Canada)
  3. Department of Radiology, Geneva University Hospital, Geneva (Switzerland)
Publication Date:
OSTI Identifier:
22423811
Resource Type:
Journal Article
Resource Relation:
Journal Name: International Journal of Radiation Oncology, Biology and Physics; Journal Volume: 90; Journal Issue: 2; Other Information: Copyright (c) 2014 Elsevier Science B.V., Amsterdam, The Netherlands, All rights reserved.; Country of input: International Atomic Energy Agency (IAEA)
Country of Publication:
United States
Language:
English
Subject:
62 RADIOLOGY AND NUCLEAR MEDICINE; COMPARATIVE EVALUATIONS; NEOPLASMS; OPTIMIZATION; PATIENTS; PROSTATE; RADIATION DOSES; RADIOTHERAPY; RECTUM; REVIEWS; SPACERS; TOXICITY