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Title: Selective and “turn-off” fluorimetric detection of mercury(II) based on coumarinyldithiolane and coumarinyldithiane in aqueous solution

Graphical abstract: Visual fluorescence emission of probe 3a. - Highlights: • Five novel coumarin-based fluorescent probes were developed. • A reasonable reaction mechanism was proposed and verified. • All the probes showed excellent optical properties. - Abstract: In this work, five novel coumarin-based fluorescent probes for mercury ions were developed. The recognition of mercury ions was performed via the mercury(II)-promoted desulfurization of the probes and a reasonable reaction mechanism was proposed and verified by thin layer chromatography (TLC), {sup 1}H nuclear magnetic resonance ({sup 1}H NMR) and fluorescence intensity measurements. All the probes showed excellent optical properties and exclusively distinguish mercury ions from various metal ions in aqueous solutions at pH 7.4. The linear response of the fluorescence emission intensity for all the probes to the concentration of mercury ions was obtained over a wide range of 0.06–1.5 μM (0.06–0.9 μM for probe 3e). In addition, the biological toxicity and the confocal fluorescence images of probe 3a were also tested on MCF-7 cells.
Authors:
 [1] ;  [2] ;  [1] ;  [3] ;  [1] ;  [4]
  1. Key Laboratory of Synthetic and Natural Functional Molecule Chemistry of Ministry of Education, College of Chemistry and Materials Science, Northwest University, 1 Xuefu Road, Xi’an 710127 (China)
  2. (France)
  3. School of Automation, Xi’an University of Posts and Telecommunications, Xi’an 710121 (China)
  4. Institut de Chimie Organique et Analytique, Université d’Orléans, 45067 Orléans Cedex 2 (France)
Publication Date:
OSTI Identifier:
22420838
Resource Type:
Journal Article
Resource Relation:
Journal Name: Materials Research Bulletin; Journal Volume: 63; Other Information: Copyright (c) 2014 Elsevier Science B.V., Amsterdam, The Netherlands, All rights reserved.; Country of input: International Atomic Energy Agency (IAEA)
Country of Publication:
United States
Language:
English
Subject:
36 MATERIALS SCIENCE; AQUEOUS SOLUTIONS; CONCENTRATION RATIO; COUMARIN; DESULFURIZATION; FLUORESCENCE; MERCURY; MERCURY IONS; NUCLEAR MAGNETIC RESONANCE; OPTICAL PROPERTIES; PH VALUE; PROBES; REACTION KINETICS; SYNTHESIS; THIN-LAYER CHROMATOGRAPHY