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Title: Some thermodynamical aspects of protein hydration water

We study by means of nuclear magnetic resonance the self-diffusion of protein hydration water at different hydration levels across a large temperature range that includes the deeply supercooled regime. Starting with a single hydration shell (h = 0.3), we consider different hydrations up to h = 0.65. Our experimental evidence indicates that two phenomena play a significant role in the dynamics of protein hydration water: (i) the measured fragile-to-strong dynamic crossover temperature is unaffected by the hydration level and (ii) the first hydration shell remains liquid at all hydrations, even at the lowest temperature.
Authors:
 [1] ;  [2] ;  [2] ;  [1] ;  [3] ;  [4] ;  [1] ;  [5] ;  [6] ;  [7]
  1. Dipartimento di Fisica e Scienze della Terra, Università di Messina and CNISM, I-98168 Messina (Italy)
  2. (United States)
  3. (Italy)
  4. Dipartimento SASTAS, Università di Messina, I-98166 Messina (Italy)
  5. CNR-IPCF, Viale F. Stagno D’Alcontres 37, I-98158 Messina (Italy)
  6. Center for Polymer Studies and Department of Physics, Boston University, Boston, Massachusetts 02215 (United States)
  7. Department of Nuclear Science and Engineering, Massachusetts Institute of Technology, Cambridge, Massachusetts 02139 (United States)
Publication Date:
OSTI Identifier:
22415955
Resource Type:
Journal Article
Resource Relation:
Journal Name: Journal of Chemical Physics; Journal Volume: 142; Journal Issue: 21; Other Information: (c) 2015 AIP Publishing LLC; Country of input: International Atomic Energy Agency (IAEA)
Country of Publication:
United States
Language:
English
Subject:
37 INORGANIC, ORGANIC, PHYSICAL AND ANALYTICAL CHEMISTRY; HYDRATION; LIQUIDS; NUCLEAR MAGNETIC RESONANCE; PROTEINS; SELF-DIFFUSION; TEMPERATURE DEPENDENCE; WATER