skip to main content

Title: The use of atlas registration and graph cuts for prostate segmentation in magnetic resonance images

Purpose: An automatic method for 3D prostate segmentation in magnetic resonance (MR) images is presented for planning image-guided radiotherapy treatment of prostate cancer. Methods: A spatial prior based on intersubject atlas registration is combined with organ-specific intensity information in a graph cut segmentation framework. The segmentation is tested on 67 axial T{sub 2}-weighted MR images in a leave-one-out cross validation experiment and compared with both manual reference segmentations and with multiatlas-based segmentations using majority voting atlas fusion. The impact of atlas selection is investigated in both the traditional atlas-based segmentation and the new graph cut method that combines atlas and intensity information in order to improve the segmentation accuracy. Best results were achieved using the method that combines intensity information, shape information, and atlas selection in the graph cut framework. Results: A mean Dice similarity coefficient (DSC) of 0.88 and a mean surface distance (MSD) of 1.45 mm with respect to the manual delineation were achieved. Conclusions: This approaches the interobserver DSC of 0.90 and interobserver MSD 0f 1.15 mm and is comparable to other studies performing prostate segmentation in MR.
Authors:
;  [1] ; ; ; ;  [2] ;  [3]
  1. Department of Health Science and Technology, Aalborg University, Aalborg 9220 (Denmark)
  2. Biomedical Imaging Group of Rotterdam, Department of Medical Informatics and Radiology, Erasmus MC, Rotterdam 3015 GE Rotterdam (Netherlands)
  3. Department of Medical Physics, Oncology, Aalborg University Hospital, Aalborg 9220 (Denmark)
Publication Date:
OSTI Identifier:
22413496
Resource Type:
Journal Article
Resource Relation:
Journal Name: Medical Physics; Journal Volume: 42; Journal Issue: 4; Other Information: (c) 2015 American Association of Physicists in Medicine; Country of input: International Atomic Energy Agency (IAEA)
Country of Publication:
United States
Language:
English
Subject:
60 APPLIED LIFE SCIENCES; ACCURACY; CALORIMETRY; COMPARATIVE EVALUATIONS; NEOPLASMS; PLANNING; PROSTATE; RADIOTHERAPY