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Title: TH-E-17A-08: Estimation of Image Quality of 4-Dimensional Computed Tomography (4DCT) Via Fourier Analysis of Corresponding 1D Breathing Surrogate

Abstract

Purpose: Motion artifacts are common in patient 4DCT, leading to an illdefined tumor volume with variation up to 110% or setting up a poor foundation with low imaging fidelity for tumor motion study. We developed a method to estimate 4DCT image quality by establishing a correlation between the severity of motion artifacts in 4DCT images and the periodicity of corresponding 1D respiratory wave-function (1DRW) surrogate used for 4DCT reconstruction. Methods: Fast Fourier Transformation (FFT) was applied to analyze 1DRW periodicity, defined as the sum of the 5 largest Fourier coefficients, ranging in 0–1. Distortional motion artifacts of cine-scan 4DCT at the junctions of adjacent couchposition scans around the diaphragm were identified in 3 categories: incomplete, overlapping and duplicate. To quantify these artifacts, the discontinuity of the diaphragm at the junctions was measured in distance and averaged along 6 directions in 3 orthogonal views. Mean and sum artifacts per junction (APJ) across the entire diaphragm were calculated in each breathing phase. To make the APJ inter-patient comparable, patientspecific motion was removed from APJ by dividing patient-specific diaphragmatic velocity (displacement divided by the mean period, from FFT analysis of the 1DRW) and the normalized APJ was defined as motion artifact severity (MAS).more » Twenty-five patients with free-breathing 10-phase 4DCT and corresponding 1DRW surrogate datasets were studied. Results: A mild correlation of 0.56 was found between 1DRW periodicity and 4DCT artifact severity. Higher MAS tends to appear around mid inhalation and mid exhalation and the lowest MAS tends to be around full exhalation. The breathing periodicity of >0.8 possesses minimal motion artifacts. Conclusion: The 1D-4D correlation provides a fast means to estimate 4DCT image quality. Using 1DRW signal, we can retrospectively screen out high-quality 4DCT images for clinical research (periodicity>0.8) and prospectively identify poor breathers as candidates of breath coaching prior to 4DCT scan. This research is in part supported by NIH (U54CA137788/132378). MC would like to thank MSKCC summer medical student research program supported by National Cancer Institute and hosted by Department of Medical Physics at MSKCC.« less

Authors:
; ; ; ;  [1];  [2]
  1. Memorial Sloan Kettering Cancer Center, New York, NY (United States)
  2. City College of New York, New York, NY (United States)
Publication Date:
OSTI Identifier:
22412520
Resource Type:
Journal Article
Journal Name:
Medical Physics
Additional Journal Information:
Journal Volume: 41; Journal Issue: 6; Other Information: (c) 2014 American Association of Physicists in Medicine; Country of input: International Atomic Energy Agency (IAEA); Journal ID: ISSN 0094-2405
Country of Publication:
United States
Language:
English
Subject:
60 APPLIED LIFE SCIENCES; COMPUTERIZED TOMOGRAPHY; NEOPLASMS; PATIENTS; PERIODICITY; RESPIRATION

Citation Formats

Caraveo, M, McNamara, J, Rimner, A, Yorke, E, Li, G, and Wei, J. TH-E-17A-08: Estimation of Image Quality of 4-Dimensional Computed Tomography (4DCT) Via Fourier Analysis of Corresponding 1D Breathing Surrogate. United States: N. p., 2014. Web. doi:10.1118/1.4889683.
Caraveo, M, McNamara, J, Rimner, A, Yorke, E, Li, G, & Wei, J. TH-E-17A-08: Estimation of Image Quality of 4-Dimensional Computed Tomography (4DCT) Via Fourier Analysis of Corresponding 1D Breathing Surrogate. United States. https://doi.org/10.1118/1.4889683
Caraveo, M, McNamara, J, Rimner, A, Yorke, E, Li, G, and Wei, J. 2014. "TH-E-17A-08: Estimation of Image Quality of 4-Dimensional Computed Tomography (4DCT) Via Fourier Analysis of Corresponding 1D Breathing Surrogate". United States. https://doi.org/10.1118/1.4889683.
@article{osti_22412520,
title = {TH-E-17A-08: Estimation of Image Quality of 4-Dimensional Computed Tomography (4DCT) Via Fourier Analysis of Corresponding 1D Breathing Surrogate},
author = {Caraveo, M and McNamara, J and Rimner, A and Yorke, E and Li, G and Wei, J},
abstractNote = {Purpose: Motion artifacts are common in patient 4DCT, leading to an illdefined tumor volume with variation up to 110% or setting up a poor foundation with low imaging fidelity for tumor motion study. We developed a method to estimate 4DCT image quality by establishing a correlation between the severity of motion artifacts in 4DCT images and the periodicity of corresponding 1D respiratory wave-function (1DRW) surrogate used for 4DCT reconstruction. Methods: Fast Fourier Transformation (FFT) was applied to analyze 1DRW periodicity, defined as the sum of the 5 largest Fourier coefficients, ranging in 0–1. Distortional motion artifacts of cine-scan 4DCT at the junctions of adjacent couchposition scans around the diaphragm were identified in 3 categories: incomplete, overlapping and duplicate. To quantify these artifacts, the discontinuity of the diaphragm at the junctions was measured in distance and averaged along 6 directions in 3 orthogonal views. Mean and sum artifacts per junction (APJ) across the entire diaphragm were calculated in each breathing phase. To make the APJ inter-patient comparable, patientspecific motion was removed from APJ by dividing patient-specific diaphragmatic velocity (displacement divided by the mean period, from FFT analysis of the 1DRW) and the normalized APJ was defined as motion artifact severity (MAS). Twenty-five patients with free-breathing 10-phase 4DCT and corresponding 1DRW surrogate datasets were studied. Results: A mild correlation of 0.56 was found between 1DRW periodicity and 4DCT artifact severity. Higher MAS tends to appear around mid inhalation and mid exhalation and the lowest MAS tends to be around full exhalation. The breathing periodicity of >0.8 possesses minimal motion artifacts. Conclusion: The 1D-4D correlation provides a fast means to estimate 4DCT image quality. Using 1DRW signal, we can retrospectively screen out high-quality 4DCT images for clinical research (periodicity>0.8) and prospectively identify poor breathers as candidates of breath coaching prior to 4DCT scan. This research is in part supported by NIH (U54CA137788/132378). MC would like to thank MSKCC summer medical student research program supported by National Cancer Institute and hosted by Department of Medical Physics at MSKCC.},
doi = {10.1118/1.4889683},
url = {https://www.osti.gov/biblio/22412520}, journal = {Medical Physics},
issn = {0094-2405},
number = 6,
volume = 41,
place = {United States},
year = {Sun Jun 15 00:00:00 EDT 2014},
month = {Sun Jun 15 00:00:00 EDT 2014}
}