skip to main content

SciTech ConnectSciTech Connect

Title: WE-D-BRF-03: Proton Beam Range Verification with a Single Prompt Gamma-Ray Detector

Purpose: To present an experimental study of a novel range verification method for scanned and scattered proton beams. Methods: A detection system consisting of an actively shielded lanthanum(III)bromide scintillator and a one-sided lead collimator was used to measure prompt gamma-rays emitted during the delivery of proton beams to a water phantom and an anthropomorphic head phantom. The residual proton range at the collimator position was determined by comparing gamma-ray intensities while the proton energy was modulated to the distal end of the target. We used a clinical field to deliver a 50 cGy dose to a 12 cm diameter target in the water phantom and to a 175 cc tumor-shaped target in the head phantom. The detector signals were acquired with a custom data acquisition system enabling energy and time-of-flight discrimination of prompt gamma-rays. Results: Range deviations were detected with a statistical accuracy of ± 0.2 mm and ± 1.4 mm at 90% confidence level, respectively for the water and head phantom. We obtained a time resolution of 1 ns FWHM and an energy resolution < 2% FWHM for the main gamma lines from proton-induced nuclear reactions with carbon and oxygen. This allowed for an accurate separation of the promptmore » gamma-rays from neutron-induced background. Conclusion: Proton range deviations can be detected with millimeter accuracy using a single prompt gamma-ray measurement point acquired during the delivery of a few proton energy layers to the distal part of the target. The method is also feasible in the presence of background radiation from passively scattered proton beam delivery.« less
Authors:
; ; ; ; ;  [1]
  1. Massachusetts General Hospital and Harvard Medical School, Boston, MA (United States)
Publication Date:
OSTI Identifier:
22407883
Resource Type:
Journal Article
Resource Relation:
Journal Name: Medical Physics; Journal Volume: 41; Journal Issue: 6; Other Information: (c) 2014 American Association of Physicists in Medicine; Country of input: International Atomic Energy Agency (IAEA)
Country of Publication:
United States
Language:
English
Subject:
60 APPLIED LIFE SCIENCES; ACCURACY; BACKGROUND RADIATION; COLLIMATORS; COMPARATIVE EVALUATIONS; DATA ACQUISITION SYSTEMS; ENERGY RESOLUTION; GAMMA RADIATION; NEOPLASMS; PHANTOMS; PROTON BEAMS; RADIATION DETECTION; RADIOTHERAPY; TIME RESOLUTION; TIME-OF-FLIGHT METHOD