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Title: Poster — Thur Eve — 74: Distributed, asynchronous, reactive dosimetric and outcomes analysis using DICOMautomaton

Many have speculated about the future of computational technology in clinical radiation oncology. It has been advocated that the next generation of computational infrastructure will improve on the current generation by incorporating richer aspects of automation, more heavily and seamlessly featuring distributed and parallel computation, and providing more flexibility toward aggregate data analysis. In this report we describe how a recently created — but currently existing — analysis framework (DICOMautomaton) incorporates these aspects. DICOMautomaton supports a variety of use cases but is especially suited for dosimetric outcomes correlation analysis, investigation and comparison of radiotherapy treatment efficacy, and dose-volume computation. We describe: how it overcomes computational bottlenecks by distributing workload across a network of machines; how modern, asynchronous computational techniques are used to reduce blocking and avoid unnecessary computation; and how issues of out-of-date data are addressed using reactive programming techniques and data dependency chains. We describe internal architecture of the software and give a detailed demonstration of how DICOMautomaton could be used to search for correlations between dosimetric and outcomes data.
Authors:
 [1] ;  [2] ;  [2] ;  [3] ;  [4] ;  [5]
  1. University of British Columbia, Vancouver, B.C. (Canada)
  2. (Canada)
  3. BC Cancer Agency, Vancouver, B.C. (Canada)
  4. University of California San Diego, La Jolla, Ca (United States)
  5. BC Cancer Agency, Surrey, B.C. (Canada)
Publication Date:
OSTI Identifier:
22407695
Resource Type:
Journal Article
Resource Relation:
Journal Name: Medical Physics; Journal Volume: 41; Journal Issue: 8; Other Information: (c) 2014 American Association of Physicists in Medicine; Country of input: International Atomic Energy Agency (IAEA)
Country of Publication:
United States
Language:
English
Subject:
60 APPLIED LIFE SCIENCES; AUTOMATION; CALCULATION METHODS; CORRELATIONS; DATA ANALYSIS; RADIATION DOSES; RADIOTHERAPY