SU-E-CAMPUS-T-02: Exploring Radiation Acoustics CT Dosimeter Design Aspects for Proton Therapy
Abstract
Purpose: Investigate the design aspects and imaging dose capabilities of the Radiation Acoustics Computed Tomography (RA CT) dosimeter for Proton induced acoustics, with the objective to characterize a pulsed pencil proton beam. The focus includes scanner geometry, transducer array, and transducer bandwidth on image quality. Methods: The geometry of the dosimeter is a cylindrical water phantom (length 40cm, radius 15cm) with 71 ultrasound transducers placed along the length and end of the cylinder to achieve a weighted set of projections with spherical sampling. A 3D filtered backprojection algorithm was used to reconstruct the dosimetric images and compared to MC dose distribution. First, 3D Monte Carlo (MC) Dose distributions for proton beam energies (range of 12cm, 16cm, 20cm, and 27cm) were used to simulate the acoustic pressure signal within this scanner for a pulsed proton beam of 1.8x107 protons, with a pulse width of 1 microsecond and a rise time of 0.1 microseconds. Dose comparison within the Bragg peak and distal edge were compared to MC analysis, where the integrated Gaussian was used to locate the 50% dose of the distal edge. To evaluate spatial fidelity, a set of point sources within the scanner field of view (15×15×15cm3) were simulated implementingmore »
- Authors:
-
- Purdue University, West Lafayette, IN (United States)
- Indiana University-School of Medicine, Indianapolis, IN (United States)
- Publication Date:
- OSTI Identifier:
- 22402263
- Resource Type:
- Journal Article
- Journal Name:
- Medical Physics
- Additional Journal Information:
- Journal Volume: 41; Journal Issue: 6; Other Information: (c) 2014 American Association of Physicists in Medicine; Country of input: International Atomic Energy Agency (IAEA); Journal ID: ISSN 0094-2405
- Country of Publication:
- United States
- Language:
- English
- Subject:
- 07 ISOTOPES AND RADIATION SOURCES; 60 APPLIED LIFE SCIENCES; ACOUSTICS; BRAGG CURVE; COMPARATIVE EVALUATIONS; COMPUTERIZED TOMOGRAPHY; DOSEMETERS; MONTE CARLO METHOD; PHANTOMS; PROTON BEAMS; PULSE RISE TIME; RADIATION DOSE DISTRIBUTIONS; RADIOTHERAPY; TRANSDUCERS
Citation Formats
Alsanea, F, Moskvin, V, Stantz, K, and Indiana University-School of Medicine, Indianapolis, IN. SU-E-CAMPUS-T-02: Exploring Radiation Acoustics CT Dosimeter Design Aspects for Proton Therapy. United States: N. p., 2014.
Web. doi:10.1118/1.4889003.
Alsanea, F, Moskvin, V, Stantz, K, & Indiana University-School of Medicine, Indianapolis, IN. SU-E-CAMPUS-T-02: Exploring Radiation Acoustics CT Dosimeter Design Aspects for Proton Therapy. United States. https://doi.org/10.1118/1.4889003
Alsanea, F, Moskvin, V, Stantz, K, and Indiana University-School of Medicine, Indianapolis, IN. 2014.
"SU-E-CAMPUS-T-02: Exploring Radiation Acoustics CT Dosimeter Design Aspects for Proton Therapy". United States. https://doi.org/10.1118/1.4889003.
@article{osti_22402263,
title = {SU-E-CAMPUS-T-02: Exploring Radiation Acoustics CT Dosimeter Design Aspects for Proton Therapy},
author = {Alsanea, F and Moskvin, V and Stantz, K and Indiana University-School of Medicine, Indianapolis, IN},
abstractNote = {Purpose: Investigate the design aspects and imaging dose capabilities of the Radiation Acoustics Computed Tomography (RA CT) dosimeter for Proton induced acoustics, with the objective to characterize a pulsed pencil proton beam. The focus includes scanner geometry, transducer array, and transducer bandwidth on image quality. Methods: The geometry of the dosimeter is a cylindrical water phantom (length 40cm, radius 15cm) with 71 ultrasound transducers placed along the length and end of the cylinder to achieve a weighted set of projections with spherical sampling. A 3D filtered backprojection algorithm was used to reconstruct the dosimetric images and compared to MC dose distribution. First, 3D Monte Carlo (MC) Dose distributions for proton beam energies (range of 12cm, 16cm, 20cm, and 27cm) were used to simulate the acoustic pressure signal within this scanner for a pulsed proton beam of 1.8x107 protons, with a pulse width of 1 microsecond and a rise time of 0.1 microseconds. Dose comparison within the Bragg peak and distal edge were compared to MC analysis, where the integrated Gaussian was used to locate the 50% dose of the distal edge. To evaluate spatial fidelity, a set of point sources within the scanner field of view (15×15×15cm3) were simulated implementing a low-pass bandwidth response function (0 to 1MHz) equivalent to a multiple frequency transducer array, and the FWHM of the point-spread-function determined. Results: From the reconstructed images, RACT and MC range values are within 0.5mm, and the average variation of the dose within the Bragg peak are within 2%. The spatial resolution tracked with transducer bandwidth and projection angle sampling, and can be kept at 1.5mm. Conclusion: This design is ready for fabrication to start acquiring measurements. The 15 cm FOV is an optimum size for imaging dosimetry. Currently, simulations comparing transducer sensitivity, bandwidth, and proton beam parameters are being evaluated to assess signal-to-noise.},
doi = {10.1118/1.4889003},
url = {https://www.osti.gov/biblio/22402263},
journal = {Medical Physics},
issn = {0094-2405},
number = 6,
volume = 41,
place = {United States},
year = {Sun Jun 15 00:00:00 EDT 2014},
month = {Sun Jun 15 00:00:00 EDT 2014}
}