Microwave-induced thermogenetic activation of single cells

Journal Article · Mon Apr 20 00:00:00 EDT 2015 · Applied Physics Letters

DOI:https://doi.org/10.1063/1.4917538· OSTI ID:22398942

Safronov, N. A. ^[1]; Fedotov, I. V. ^[1]; Ermakova, Yu. G.; Matlashov, M. E.; Belousov, V. V. ^[2]; Sidorov-Biryukov, D. A.; Fedotov, A. B. ^[1]; Zheltikov, A. M. ^[1]

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1. Physics Department, International Laser Center, M.V. Lomonosov Moscow State University, Moscow 119992 (Russian Federation)
2. M.M. Shemyakin and Yu.A. Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Sciences, Moscow 117997 (Russian Federation)

Exposure to a microwave field is shown to enable thermogenetic activation of individual cells in a culture of cell expressing thermosensitive ion channels. Integration of a microwave transmission line with an optical fiber and a diamond quantum thermometer has been shown to allow thermogenetic single-cell activation to be combined with accurate local online temperature measurements based on an optical detection of electron spin resonance in nitrogen–vacancy centers in diamond.

• OSTI ID: 22398942
• Journal Information: Applied Physics Letters, Vol. 106, Issue 16; Other Information: (c) 2015 AIP Publishing LLC; Country of input: International Atomic Energy Agency (IAEA); ISSN 0003-6951
• Country of Publication: United States
• Language: English

Related Subjects

71 CLASSICAL AND QUANTUM MECHANICS
GENERAL PHYSICS
DETECTION
DIAMONDS
ELECTRON SPIN RESONANCE
IONS
MICROWAVE RADIATION
NITROGEN
OPTICAL FIBERS
POWER TRANSMISSION LINES
TEMPERATURE MEASUREMENT
THERMOMETERS
VACANCIES