Optical diagnostics of vascular reactions triggered by weak allergens using laser speckle-contrast imaging technique

Journal Article · Sun Aug 31 00:00:00 EDT 2014 · Quantum Electronics (Woodbury, N.Y.)

DOI:https://doi.org/10.1070/QE2014V044N08ABEH015489· OSTI ID:22395819

Kuznetsov, Yu L; Kalchenko, V V ^[1]; Astaf'eva, N G ^[2]; Meglinski, I V ^[3]

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1. Department of Veterinary Resources, Weizmann Institute of Science, Rehovot, 76100 (Israel)
2. V.I.Razumovsky Saratov State Medical University, Saratov (Russian Federation)
3. N.G. Chernyshevsky Saratov State University, Saratov (Russian Federation)

The capability of using the laser speckle contrast imaging technique with a long exposure time for visualisation of primary acute skin vascular reactions caused by a topical application of a weak contact allergen is considered. The method is shown to provide efficient and accurate detection of irritant-induced primary acute vascular reactions of skin. The presented technique possesses a high potential in everyday diagnostic practice, preclinical studies, as well as in the prognosis of skin reactions to the interaction with potentially allergenic materials. (laser biophotonics)

• OSTI ID: 22395819
• Journal Information: Quantum Electronics (Woodbury, N.Y.), Vol. 44, Issue 8; Other Information: Country of input: International Atomic Energy Agency (IAEA); ISSN 1063-7818
• Country of Publication: United States
• Language: English

Related Subjects

62 RADIOLOGY AND NUCLEAR MEDICINE
ALLERGY
DIAGNOSIS
IMAGES
LASERS
SKIN