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Title: Rapid and noncontact photoacoustic tomography imaging system using an interferometer with high-speed phase modulation technique

We designed, fabricated, and tested a rapid and noncontact photoacoustic tomography (PAT) imaging system using a low-coherence interferometer with high-speed phase modulation technique. Such a rapid and noncontact probing system can greatly decrease the time of imaging. The proposed PAT imaging system is experimentally verified by capturing images of a simulated tissue sample and the blood vessels within the ear flap of a mouse (pinna) in vivo. The axial and lateral resolutions of the system are evaluated at 45 and ∼15 μm, respectively. The imaging depth of the system is 1 mm in a special phantom. Our results show that the proposed system opens a promising way to realize noncontact, real-time PAT.
Authors:
 [1] ; ;  [1] ;  [2] ;  [3]
  1. School of Physics and Telecom Engineering, South China Normal University, Guangzhou 510006 (China)
  2. (China)
  3. School of Control Engineering, Northeastern University at Qinhuangdao, Qinhuangdao 066004 (China)
Publication Date:
OSTI Identifier:
22392471
Resource Type:
Journal Article
Resource Relation:
Journal Name: Review of Scientific Instruments; Journal Volume: 86; Journal Issue: 4; Other Information: (c) 2015 AIP Publishing LLC; Country of input: International Atomic Energy Agency (IAEA)
Country of Publication:
United States
Language:
English
Subject:
46 INSTRUMENTATION RELATED TO NUCLEAR SCIENCE AND TECHNOLOGY; ANIMAL TISSUES; AUDITORY ORGANS; BLOOD VESSELS; IN VIVO; INTERFEROMETERS; MICE; MODULATION; PHANTOMS; RESOLUTION; SIMULATION; TOMOGRAPHY