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Title: A novel experimental approach to investigate radiolysis processes in liquid samples using collimated radiation sources

Here is detailed a novel and low-cost experimental method for high-throughput automated fluid sample irradiation. The sample is delivered via syringe pump to a nozzle, where it is expressed in the form of a hanging droplet into the path of a beam of ionising radiation. The dose delivery is controlled by an upstream lead shutter, which allows the beam to reach the droplet for a user defined period of time. The droplet is then further expressed after irradiation until it falls into one well of a standard microplate. The entire system is automated and can be operated remotely using software designed in-house, allowing for use in environments deemed unsafe for the user (synchrotron beamlines, for example). Depending on the number of wells in the microplate, several droplets can be irradiated before any human interaction is necessary, and the user may choose up to 10 samples per microplate using an array of identical syringe pumps, the design of which is described here. The nozzles consistently produce droplets of 25.1 ± 0.5 μl.
Authors:
; ; ; ; ; ; ;  [1] ;  [2] ; ; ;  [3]
  1. Department of Mathematics and Physics, Centre for Plasma Physics, Queen’s University Belfast, Belfast (United Kingdom)
  2. School of Physics and Astronomy, University of Manchester, Manchester (United Kingdom)
  3. Laboratoire de Chimie Physique, Université Paris-Sud, Orsay (France)
Publication Date:
OSTI Identifier:
22392430
Resource Type:
Journal Article
Resource Relation:
Journal Name: Review of Scientific Instruments; Journal Volume: 86; Journal Issue: 3; Other Information: (c) 2015 AIP Publishing LLC; Country of input: International Atomic Energy Agency (IAEA)
Country of Publication:
United States
Language:
English
Subject:
46 INSTRUMENTATION RELATED TO NUCLEAR SCIENCE AND TECHNOLOGY; DESIGN; DROPLETS; IRRADIATION; LIQUIDS; NOZZLES; RADIATION SOURCES; RADIOLYSIS; SYNCHROTRONS