skip to main content

Title: 3D parallel-detection microwave tomography for clinical breast imaging

A biomedical microwave tomography system with 3D-imaging capabilities has been constructed and translated to the clinic. Updates to the hardware and reconfiguration of the electronic-network layouts in a more compartmentalized construct have streamlined system packaging. Upgrades to the data acquisition and microwave components have increased data-acquisition speeds and improved system performance. By incorporating analog-to-digital boards that accommodate the linear amplification and dynamic-range coverage our system requires, a complete set of data (for a fixed array position at a single frequency) is now acquired in 5.8 s. Replacement of key components (e.g., switches and power dividers) by devices with improved operational bandwidths has enhanced system response over a wider frequency range. High-integrity, low-power signals are routinely measured down to −130 dBm for frequencies ranging from 500 to 2300 MHz. Adequate inter-channel isolation has been maintained, and a dynamic range >110 dB has been achieved for the full operating frequency range (500–2900 MHz). For our primary band of interest, the associated measurement deviations are less than 0.33% and 0.5° for signal amplitude and phase values, respectively. A modified monopole antenna array (composed of two interwoven eight-element sub-arrays), in conjunction with an updated motion-control system capable of independently moving the sub-arrays to variousmore » in-plane and cross-plane positions within the illumination chamber, has been configured in the new design for full volumetric data acquisition. Signal-to-noise ratios (SNRs) are more than adequate for all transmit/receive antenna pairs over the full frequency range and for the variety of in-plane and cross-plane configurations. For proximal receivers, in-plane SNRs greater than 80 dB are observed up to 2900 MHz, while cross-plane SNRs greater than 80 dB are seen for 6 cm sub-array spacing (for frequencies up to 1500 MHz). We demonstrate accurate recovery of 3D dielectric property distributions for breast-like phantoms with tumor inclusions utilizing both the in-plane and new cross-plane data.« less
Authors:
 [1] ;  [2] ;  [2] ;  [3] ;  [3] ;  [3]
  1. Schulich School of Engineering, University of Calgary, 2500 University Dr. NW, Calgary, Alberta T2N 1N4 (Canada)
  2. Thayer School of Engineering, Dartmouth College, 14 Engineering Dr., Hanover, New Hampshire 03755 (United States)
  3. (United States)
Publication Date:
OSTI Identifier:
22392289
Resource Type:
Journal Article
Resource Relation:
Journal Name: Review of Scientific Instruments; Journal Volume: 85; Journal Issue: 12; Other Information: (c) 2014 AIP Publishing LLC; Country of input: International Atomic Energy Agency (IAEA)
Country of Publication:
United States
Language:
English
Subject:
46 INSTRUMENTATION RELATED TO NUCLEAR SCIENCE AND TECHNOLOGY; ANTENNAS; DATA ACQUISITION; DETECTION; DIELECTRIC PROPERTIES; MAMMARY GLANDS; MHZ RANGE; MICROWAVE RADIATION; NEOPLASMS; PHANTOMS; SIGNALS; SIGNAL-TO-NOISE RATIO; SWITCHES; TOMOGRAPHY