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Title: Structural morphology of zinc oxide structures with antibacterial application of calamine lotion

In this study, we report the structural morphology of a zinc oxide (ZnO) sample and antibacterial application of the ZnO structures in calamine lotion. Antibacterial activities of the calamine lotion towards Staphylococcus aureus and Pseudomonas aeruginosa were investigated. The structural morphology of ZnO sample was studied using a transmission electron microscope (TEM) and a field-emission scanning electron microscope (FESEM). The morphologies of the ZnO structure consisted of many rod and spherical structures. The particle sizes of the sample ranged from 40 nm to 150 nm. A calamine lotion was prepared through mixing the ZnO structures with other constituents in suitable proportion. The energy-dispersive x-ray spectroscopy (EDS) revealed the presence of large amount of ZnO structures whiles the X-ray diffraction (XRD) results showed a good crystalline property of ZnO in the calamine lotion mixture. The morphological structures of ZnO were found to remain unchanged in the calamine lotion mixture through FESEM imaging. In the antibacterial test, prepared calamine lotion exhibited a remarkable bacterial inhibition on Staphylococcus aureus and Pseudomonas aeruginosa after 24 h of treatment. The bactericidal capability of calamine lotion was largely due to the presence of ZnO structures which induce high toxicity and killing effect on the bacteria.
Authors:
; ; ;  [1] ;  [2] ; ;  [3] ;  [4]
  1. Nano-optoelectronic Research (NOR) Laboratory, School of Physics, Universiti Sains Malaysia 11800 Pulau Pinang (Malaysia)
  2. School of Dental Sciences, Universiti Sains Malaysia, Kubang Kerian 16150 Kelantan (Malaysia)
  3. School of Medical Sciences, Universiti Sains Malaysia, Kubang Kerian 16150 Kelantan (Malaysia)
  4. Advanced Medical and Dental Institute, Universiti Sains Malaysia, Bertam 13200 Pulau Pinang (Malaysia)
Publication Date:
OSTI Identifier:
22391543
Resource Type:
Journal Article
Resource Relation:
Journal Name: AIP Conference Proceedings; Journal Volume: 1657; Journal Issue: 1; Conference: PERFIK 2014: National Physics Conference 2014, Kuala Lumpur (Malaysia), 18-19 Nov 2014; Other Information: (c) 2015 AIP Publishing LLC; Country of input: International Atomic Energy Agency (IAEA)
Country of Publication:
United States
Language:
English
Subject:
36 MATERIALS SCIENCE; 60 APPLIED LIFE SCIENCES; CUBIC LATTICES; FIELD EMISSION; MORPHOLOGY; PARTICLE SIZE; PSEUDOMONAS; SCANNING ELECTRON MICROSCOPY; STAPHYLOCOCCUS; TRANSMISSION ELECTRON MICROSCOPY; X-RAY DIFFRACTION; X-RAY SPECTROSCOPY; ZINC OXIDES