skip to main content

SciTech ConnectSciTech Connect

Title: Monte Carlo simulation of an x-ray luminescence optical tomography scanner prototype

In this work we report the calculation of the deposited energy distribution produced by an x-ray luminescence optical tomography (XLOT) system in a phantom containing different concentrations of Gd{sub 2}O{sub 2}S:Eu nanoparticles. The calculations were performed via Monte Carlo simulation considering spectra from a W target x-ray tube operating between 30 and 90 kVp, with 1.0 mm Al added filtration. CT and XLOT tomographic images were reconstructed from the same data. The results show that XLOT has better detectability than CT alone, that the dose scales linearly with kVp for a fixed concentration of Gd{sub 2}O{sub 2}S:Eu and air-kerma rate, the scattered radiation contribution to the total dose and signal is about 20% and that the dose ratio for a 3 mm diameter insert containing 10 mg/ml Gd{sub 2}O{sub 2}S embedded in a 30 mm diameter water phantom is 6:1. This ratio drops to less than 2:1 for a 1 mg/ml concentration. Finally we show that the method of conjugate images can be used to correct for artifacts due to attenuation effects in XLOT images.
Authors:
; ; ;  [1]
  1. Instituto de Física, Universidad Nacional Autónoma de México, A.P. 20-364, 01000 (Mexico)
Publication Date:
OSTI Identifier:
22390517
Resource Type:
Journal Article
Resource Relation:
Journal Name: AIP Conference Proceedings; Journal Volume: 1626; Journal Issue: 1; Conference: 13. Mexican Symposium on Medical Physics, Leon, Guanajuato (Mexico), 15-16 Mar 2014; Other Information: (c) 2014 AIP Publishing LLC; Country of input: International Atomic Energy Agency (IAEA)
Country of Publication:
United States
Language:
English
Subject:
71 CLASSICAL AND QUANTUM MECHANICS, GENERAL PHYSICS; 60 APPLIED LIFE SCIENCES; ATTENUATION; COMPUTERIZED SIMULATION; COMPUTERIZED TOMOGRAPHY; CONCENTRATION RATIO; ENERGY SPECTRA; IMAGES; KERMA; LUMINESCENCE; MONTE CARLO METHOD; NANOPARTICLES; PHANTOMS; RADIATION DOSES; X RADIATION; X-RAY TUBES