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Title: Porosity and biocompatibility study of ceramic implants based on ZrO{sub 2} and Al{sub 2}O{sub 3}

The work studies ZrO{sub 2}(Me{sub x}O{sub y})-based porous ceramics produced from the powders consisting of hollow spherical particles. It was shown that the structure is represented by a cellular framework with bimodal porosity consisting of sphere-like large pores and pores that were not filled with the powder particles during the compaction. For such ceramics, the increase of pore volume is accompanied by the increased strain in an elastic area. It was also shown that the porous ZrO{sub 2} ceramics had no acute or chronic cytotoxicity. At the same time, ceramics possess the following osteoconductive properties: adhesion support, spreading, proliferation and osteogenic differentiation of MSCs.
Authors:
; ;  [1] ; ;  [2] ; ;  [3] ;  [4] ;  [4]
  1. Immanuel Kant Baltic Federal University, Kaliningrad (Russian Federation)
  2. State Institute of Genetic and Regenerative Medicine, National Academy of Medical Sciences of Ukraine, Kiev (Ukraine)
  3. Institute of Strength Physics and Materials Science SB RAS, Tomsk, 634055 (Russian Federation)
  4. (Russian Federation)
Publication Date:
OSTI Identifier:
22390419
Resource Type:
Journal Article
Resource Relation:
Journal Name: AIP Conference Proceedings; Journal Volume: 1623; Journal Issue: 1; Conference: International Conference on Physical Mesomechanics of Multilevel Systems 2014, Tomsk (Russian Federation), 3-5 Sep 2014; Other Information: (c) 2014 AIP Publishing LLC; Country of input: International Atomic Energy Agency (IAEA)
Country of Publication:
United States
Language:
English
Subject:
36 MATERIALS SCIENCE; ADHESION; ALUMINIUM OXIDES; CERAMICS; CRYSTAL STRUCTURE; IMPLANTS; POROSITY; POROUS MATERIALS; POWDERS; SPHERES; SPHERICAL CONFIGURATION; STRAINS; TOXICITY; ZIRCONIUM OXIDES