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Title: Theoretical limit of spatial resolution in diffuse optical tomography using a perturbation model

We have assessed the limit of spatial resolution of timedomain diffuse optical tomography (DOT) based on a perturbation reconstruction model. From the viewpoint of the structure reconstruction accuracy, three different approaches to solving the inverse DOT problem are compared. The first approach involves reconstruction of diffuse tomograms from straight lines, the second – from average curvilinear trajectories of photons and the third – from total banana-shaped distributions of photon trajectories. In order to obtain estimates of resolution, we have derived analytical expressions for the point spread function and modulation transfer function, as well as have performed a numerical experiment on reconstruction of rectangular scattering objects with circular absorbing inhomogeneities. It is shown that in passing from reconstruction from straight lines to reconstruction using distributions of photon trajectories we can improve resolution by almost an order of magnitude and exceed the accuracy of reconstruction of multi-step algorithms used in DOT. (optical tomography)
Authors:
;  [1]
  1. E.I. Zababakhin All-Russian Scientific-Research Institute of Technical Physics, Russian Federal Nuclear Centre, Snezhinsk, Chelyabinsk region (Russian Federation)
Publication Date:
OSTI Identifier:
22375956
Resource Type:
Journal Article
Resource Relation:
Journal Name: Quantum Electronics (Woodbury, N.Y.); Journal Volume: 44; Journal Issue: 3; Other Information: Country of input: International Atomic Energy Agency (IAEA)
Country of Publication:
United States
Language:
English
Subject:
72 PHYSICS OF ELEMENTARY PARTICLES AND FIELDS; ALGORITHMS; DISTRIBUTION; DISTURBANCES; MODULATION; PHOTONS; SCATTERING; SIMULATION; SPATIAL RESOLUTION; TOMOGRAPHY; TRAJECTORIES; TRANSFER FUNCTIONS