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Title: SU-E-T-208: Incidence Cancer Risk From the Radiation Treatment for Acoustic Neuroma Patient

Purpose: The present study aimed to compare the incidence risk of a secondary cancer from therapeutic doses in patients receiving intensitymodulated radiotherapy (IMRT), volumetric modulated arc therapy (VMAT), and stereotactic radiosurgery (SRS). Methods: Four acoustic neuroma patients were treated with IMRT, VMAT, or SRS. Their incidnece excess relative risk (ERR), excess absolute risk (EAR), and lifetime attributable risk (LAR) were estimated using the corresponding therapeutic doses measured at various organs by radio-photoluminescence glass dosimeters (RPLGD) placed inside a humanoid phantom. Results: When a prescription dose was delivered in the planning target volume of the 4 patients, the average organ equivalent doses (OED) at the thyroid, lung, normal liver, colon, bladder, prostate (or ovary), and rectum were measured. The OED decreased as the distance from the primary beam increased. The thyroid received the highest OED compared to other organs. A LAR were estimated that more than 0.03% of AN patients would get radiation-induced cancer. Conclusion: The tyroid was highest radiation-induced cancer risk after radiation treatment for AN. We found that LAR can be increased by the transmitted dose from the primary beam. No modality-specific difference in radiation-induced cancer risk was observed in our study.
Authors:
 [1] ;  [2] ;  [3] ;  [4]
  1. Kyung Hee University International Med. Serv., Seoul (Korea, Republic of)
  2. Kyung Hee University Hospital at Gangdong, Seoul, Seoul (Korea, Republic of)
  3. Kyung Hee University Hospital, Seoul, Seoul (Korea, Republic of)
  4. Korea University, Seoul (Korea, Republic of)
Publication Date:
OSTI Identifier:
22351044
Resource Type:
Journal Article
Resource Relation:
Journal Name: Medical Physics; Journal Volume: 41; Journal Issue: 6; Other Information: (c) 2014 American Association of Physicists in Medicine; Country of input: International Atomic Energy Agency (IAEA)
Country of Publication:
United States
Language:
English
Subject:
60 APPLIED LIFE SCIENCES; 62 RADIOLOGY AND NUCLEAR MEDICINE; BLADDER; HEALTH HAZARDS; LIVER; LUNGS; NEOPLASMS; OVARIES; PATIENTS; PHANTOMS; PHOTOLUMINESCENCE; PROSTATE; RADIATION DOSES; RADIOTHERAPY; RECTUM; THYROID