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Title: SU-E-T-208: Incidence Cancer Risk From the Radiation Treatment for Acoustic Neuroma Patient

Abstract

Purpose: The present study aimed to compare the incidence risk of a secondary cancer from therapeutic doses in patients receiving intensitymodulated radiotherapy (IMRT), volumetric modulated arc therapy (VMAT), and stereotactic radiosurgery (SRS). Methods: Four acoustic neuroma patients were treated with IMRT, VMAT, or SRS. Their incidnece excess relative risk (ERR), excess absolute risk (EAR), and lifetime attributable risk (LAR) were estimated using the corresponding therapeutic doses measured at various organs by radio-photoluminescence glass dosimeters (RPLGD) placed inside a humanoid phantom. Results: When a prescription dose was delivered in the planning target volume of the 4 patients, the average organ equivalent doses (OED) at the thyroid, lung, normal liver, colon, bladder, prostate (or ovary), and rectum were measured. The OED decreased as the distance from the primary beam increased. The thyroid received the highest OED compared to other organs. A LAR were estimated that more than 0.03% of AN patients would get radiation-induced cancer. Conclusion: The tyroid was highest radiation-induced cancer risk after radiation treatment for AN. We found that LAR can be increased by the transmitted dose from the primary beam. No modality-specific difference in radiation-induced cancer risk was observed in our study.

Authors:
 [1];  [2];  [3];  [4]
  1. Kyung Hee University International Med. Serv., Seoul (Korea, Republic of)
  2. Kyung Hee University Hospital at Gangdong, Seoul, Seoul (Korea, Republic of)
  3. Kyung Hee University Hospital, Seoul, Seoul (Korea, Republic of)
  4. Korea University, Seoul (Korea, Republic of)
Publication Date:
OSTI Identifier:
22351044
Resource Type:
Journal Article
Journal Name:
Medical Physics
Additional Journal Information:
Journal Volume: 41; Journal Issue: 6; Other Information: (c) 2014 American Association of Physicists in Medicine; Country of input: International Atomic Energy Agency (IAEA); Journal ID: ISSN 0094-2405
Country of Publication:
United States
Language:
English
Subject:
60 APPLIED LIFE SCIENCES; 62 RADIOLOGY AND NUCLEAR MEDICINE; BLADDER; HEALTH HAZARDS; LIVER; LUNGS; NEOPLASMS; OVARIES; PATIENTS; PHANTOMS; PHOTOLUMINESCENCE; PROSTATE; RADIATION DOSES; RADIOTHERAPY; RECTUM; THYROID

Citation Formats

Kim, D, Chung, W, Shin, D, and Yoon, M. SU-E-T-208: Incidence Cancer Risk From the Radiation Treatment for Acoustic Neuroma Patient. United States: N. p., 2014. Web. doi:10.1118/1.4888538.
Kim, D, Chung, W, Shin, D, & Yoon, M. SU-E-T-208: Incidence Cancer Risk From the Radiation Treatment for Acoustic Neuroma Patient. United States. https://doi.org/10.1118/1.4888538
Kim, D, Chung, W, Shin, D, and Yoon, M. 2014. "SU-E-T-208: Incidence Cancer Risk From the Radiation Treatment for Acoustic Neuroma Patient". United States. https://doi.org/10.1118/1.4888538.
@article{osti_22351044,
title = {SU-E-T-208: Incidence Cancer Risk From the Radiation Treatment for Acoustic Neuroma Patient},
author = {Kim, D and Chung, W and Shin, D and Yoon, M},
abstractNote = {Purpose: The present study aimed to compare the incidence risk of a secondary cancer from therapeutic doses in patients receiving intensitymodulated radiotherapy (IMRT), volumetric modulated arc therapy (VMAT), and stereotactic radiosurgery (SRS). Methods: Four acoustic neuroma patients were treated with IMRT, VMAT, or SRS. Their incidnece excess relative risk (ERR), excess absolute risk (EAR), and lifetime attributable risk (LAR) were estimated using the corresponding therapeutic doses measured at various organs by radio-photoluminescence glass dosimeters (RPLGD) placed inside a humanoid phantom. Results: When a prescription dose was delivered in the planning target volume of the 4 patients, the average organ equivalent doses (OED) at the thyroid, lung, normal liver, colon, bladder, prostate (or ovary), and rectum were measured. The OED decreased as the distance from the primary beam increased. The thyroid received the highest OED compared to other organs. A LAR were estimated that more than 0.03% of AN patients would get radiation-induced cancer. Conclusion: The tyroid was highest radiation-induced cancer risk after radiation treatment for AN. We found that LAR can be increased by the transmitted dose from the primary beam. No modality-specific difference in radiation-induced cancer risk was observed in our study.},
doi = {10.1118/1.4888538},
url = {https://www.osti.gov/biblio/22351044}, journal = {Medical Physics},
issn = {0094-2405},
number = 6,
volume = 41,
place = {United States},
year = {Sun Jun 01 00:00:00 EDT 2014},
month = {Sun Jun 01 00:00:00 EDT 2014}
}