The Protein Information Management System (PiMS): a generic tool for any structural biology research laboratory

Journal Article · Fri Apr 01 00:00:00 EDT 2011 · Acta Crystallographica. Section D: Biological Crystallography

DOI:https://doi.org/10.1107/S0907444911007943· OSTI ID:22347919

Morris, Chris ^[1]; Pajon, Anne ^[2]; Griffiths, Susanne L. ^[3]; Daniel, Ed ^[1]; Savitsky, Marc ^[4]; Lin, Bill ^[1]; Diprose, Jonathan M. ^[4]; Wilter da Silva, Alan ^[2]; Pilicheva, Katya ^[4]; Troshin, Peter ^[1]; Niekerk, Johannes van ^[5]; Isaacs, Neil ^[6]; Naismith, James ^[7]; Nave, Colin; Blake, Richard ^[1]; Wilson, Keith S. ^[3]; Stuart, David I. ^[4]; Henrick, Kim ^[2]

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1. STFC Daresbury Laboratory, Warrington WA4 4AD (United Kingdom)
2. Wellcome Trust Genome Campus, Hinxton CB10 1SD (United Kingdom)
3. University of York, Heslington, York YO10 5DD (United Kingdom)
4. University of Oxford, Roosevelt Drive, Oxford OX3 7BN (United Kingdom)
5. University of Dundee, Dundee DD1 5EH, Scotland (United Kingdom)
6. University of Glasgow, Glasgow G12 8QQ, Scotland (United Kingdom)
7. University of St Andrews, St Andrews, Fife KY16 9ST, Scotland (United Kingdom)

The Protein Information Management System (PiMS) is described together with a discussion of how its features make it well suited to laboratories of all sizes. The techniques used in protein production and structural biology have been developing rapidly, but techniques for recording the laboratory information produced have not kept pace. One approach is the development of laboratory information-management systems (LIMS), which typically use a relational database schema to model and store results from a laboratory workflow. The underlying philosophy and implementation of the Protein Information Management System (PiMS), a LIMS development specifically targeted at the flexible and unpredictable workflows of protein-production research laboratories of all scales, is described. PiMS is a web-based Java application that uses either Postgres or Oracle as the underlying relational database-management system. PiMS is available under a free licence to all academic laboratories either for local installation or for use as a managed service.

• OSTI ID: 22347919
• Journal Information: Acta Crystallographica. Section D: Biological Crystallography, Vol. 67, Issue Pt 4; Other Information: PMCID: PMC3069740; PMID: 21460443; PUBLISHER-ID: ba5164; OAI: oai:pubmedcentral.nih.gov:3069740; Copyright (c) Morris et al. 2011; This is an open-access article distributed under the terms of the Creative Commons Attribution Licence, which permits unrestricted use, distribution, and reproduction in any medium, provided the original authors and source are cited.; Country of input: International Atomic Energy Agency (IAEA); ISSN 0907-4449
• Country of Publication: Denmark
• Language: English

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