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Title: SU-E-J-71: Feasibility Study On MRI-Based BANG3 Gel Dosimetry Using Dual-Source Parallel RF Transmission System

Purpose: In this work, we present the feasibility of use of the parallel RF transmission with multiple RF source (MultiTransmit) imaging in MRI-based polymer gel dosimetry. Methods: The commercially available BANG3 gel was used for gel dosimetry. Spin-spin relaxation rate R2 was used to quantify the absorbed dose. The image quality (signal-to-noise ratio, SNR; image uniformity) and B1 field inhomogeneity between conventional single-source and MultiTransmit MR imaging were compared. Finally, the estimated R2 uncertainty σ(R2) and dosimetric performance (i.e., dose resolution) between conventional single-source and MultiTransmit MR imaging were compared. Results: Image quality and B1 field homogeneity within each calibration vial and large phantom was statistically better in MultiTransmit imaging than in conventional single-source RF transmission imaging (P < 0.005 for all calibration vials). In particular, σ(R2) (defined as the standard uncertainty of R2) was lower on the MultiTransmit images than on the conventional single-source images. Furthermore, the MultiTransmit measurement gives a lower than that obtained using the conventional single-source method. Conclusion: The improved image quality and B1 homogeneity resulted in reduced dose uncertainty (i.e., σ(R2) and dose resolution) in MRI-based polymer gel dosimetry, suggesting that MultiTransmit MR imaging has potential benefits for use in clinical 3D gel dosimetry withoutmore » the need for the complicated B1 field correction method.« less
Authors:
; ; ; ;  [1] ;  [2]
  1. The Catholic University of Korea, Seoul, Seoul (Korea, Republic of)
  2. Korea Basic Science Institute, Chungwon, Chungwon (Korea, Republic of)
Publication Date:
OSTI Identifier:
22325229
Resource Type:
Journal Article
Resource Relation:
Journal Name: Medical Physics; Journal Volume: 41; Journal Issue: 6; Other Information: (c) 2014 American Association of Physicists in Medicine; Country of input: International Atomic Energy Agency (IAEA)
Country of Publication:
United States
Language:
English
Subject:
46 INSTRUMENTATION RELATED TO NUCLEAR SCIENCE AND TECHNOLOGY; ABSORBED RADIATION DOSES; CALIBRATION; CORRECTIONS; GELS; IMAGES; NMR IMAGING; PERFORMANCE; POLYMER GEL DOSIMETRY; RESOLUTION; SIGNAL-TO-NOISE RATIO; SPIN-SPIN RELAXATION