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Title: High sensitivity and high Q-factor nanoslotted parallel quadrabeam photonic crystal cavity for real-time and label-free sensing

We experimentally demonstrate a label-free sensor based on nanoslotted parallel quadrabeam photonic crystal cavity (NPQC). The NPQC possesses both high sensitivity and high Q-factor. We achieved sensitivity (S) of 451 nm/refractive index unit and Q-factor >7000 in water at telecom wavelength range, featuring a sensor figure of merit >2000, an order of magnitude improvement over the previous photonic crystal sensors. In addition, we measured the streptavidin-biotin binding affinity and detected 10 ag/mL concentrated streptavidin in the phosphate buffered saline solution.
Authors:
 [1] ;  [2] ;  [3] ; ; ;  [4] ; ;  [1] ; ;  [5]
  1. Rowland Institute at Harvard University, Cambridge, Massachusetts 02142 (United States)
  2. (China)
  3. (United States)
  4. School of Engineering and Applied Sciences, Harvard University, Cambridge, Massachusetts 02138 (United States)
  5. State Key Laboratory of Information Photonics and Optical Communications, School of Information and Communication Engineering, Beijing University of Posts and Telecommunications, Beijing 100876 (China)
Publication Date:
OSTI Identifier:
22318019
Resource Type:
Journal Article
Resource Relation:
Journal Name: Applied Physics Letters; Journal Volume: 105; Journal Issue: 6; Other Information: (c) 2014 AIP Publishing LLC; Country of input: International Atomic Energy Agency (IAEA)
Country of Publication:
United States
Language:
English
Subject:
71 CLASSICAL AND QUANTUM MECHANICS, GENERAL PHYSICS; BIOTIN; CRYSTALS; NANOSTRUCTURES; PERFORMANCE; PHOSPHATES; REFRACTIVE INDEX; SENSORS