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Title: Oscillations in probability distributions for stochastic gene expression

The phenomenon of oscillations in probability distribution functions of number of components is found for a model of stochastic gene expression. It takes place in cases of low levels of molecules or strong intracellular noise. The oscillations distinguish between more probable even and less probable odd number of particles. The even-odd symmetry restores as the number of molecules increases with the probability distribution function tending to Poisson distribution. We discuss the possibility of observation of the phenomenon in gene, protein, and mRNA expression experiments.
Authors:
;  [1]
  1. Institute of Physics, Academia Sinica, Nankang, Taipei 11529, Taiwan (China)
Publication Date:
OSTI Identifier:
22304346
Resource Type:
Journal Article
Resource Relation:
Journal Name: Journal of Chemical Physics; Journal Volume: 140; Journal Issue: 20; Other Information: (c) 2014 AIP Publishing LLC; Country of input: International Atomic Energy Agency (IAEA)
Country of Publication:
United States
Language:
English
Subject:
60 APPLIED LIFE SCIENCES; 37 INORGANIC, ORGANIC, PHYSICAL AND ANALYTICAL CHEMISTRY; DISTRIBUTION FUNCTIONS; GENES; MESSENGER-RNA; MOLECULES; OSCILLATIONS; PARTICLES; PROBABILITY; PROTEINS; STOCHASTIC PROCESSES