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Title: Source localization of brain activity using helium-free interferometer

To detect extremely small magnetic fields generated by the human brain, currently all commercial magnetoencephalography (MEG) systems are equipped with low-temperature (low-T{sub c}) superconducting quantum interference device (SQUID) sensors that use liquid helium for cooling. The limited and increasingly expensive supply of helium, which has seen dramatic price increases recently, has become a real problem for such systems and the situation shows no signs of abating. MEG research in the long run is now endangered. In this study, we report a MEG source localization utilizing a single, highly sensitive SQUID cooled with liquid nitrogen only. Our findings confirm that localization of neuromagnetic activity is indeed possible using high-T{sub c} SQUIDs. We believe that our findings secure the future of this exquisitely sensitive technique and have major implications for brain research and the developments of cost-effective multi-channel, high-T{sub c} SQUID-based MEG systems.
Authors:
; ; ;  [1] ; ;  [2] ;  [1] ;  [3] ;  [4]
  1. Institute of Neuroscience and Medicine (INM-4), Forschungszentrum Jülich, Jülich (Germany)
  2. Peter Grünberg Institute (PGI-5), Forschungszentrum Jülich, Jülich (Germany)
  3. (Germany)
  4. (JARA)—Translational Brain Medicine, Jülich (Germany)
Publication Date:
OSTI Identifier:
22300119
Resource Type:
Journal Article
Resource Relation:
Journal Name: Applied Physics Letters; Journal Volume: 104; Journal Issue: 21; Other Information: (c) 2014 AIP Publishing LLC; Country of input: International Atomic Energy Agency (IAEA)
Country of Publication:
United States
Language:
English
Subject:
71 CLASSICAL AND QUANTUM MECHANICS, GENERAL PHYSICS; BRAIN; COOLING; CURRENTS; EQUIPMENT; HIGH-TC SUPERCONDUCTORS; INTERFEROMETERS; LIQUIDS; MAGNETIC FIELDS; MEN; SENSORS; SQUID DEVICES