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Title: Pressure-driven fast reaction and recovery of peptide receptor for an electronic nose application

Combining a highly sensitive sensor platform with highly selective recognition elements is essential for micro/nanotechnology-based electronic nose applications. Particularly, the regeneration sensor surface and its conditions are key issues for practical e-nose applications. We propose a highly sensitive piezoelectric-driven microcantilever array chip with highly selective peptide receptors. By utilizing the peptide receptor, which was discovered by a phase display screening process, we immobilized a dinitrotoluene (DNT) specific peptide as well as a DNT nonspecific peptide on the surface of the cantilever array. The delivery of DNT gas via pressure-driven flow led to a greater instant response of ∼30 Hz, compared to diffusion only (∼15 Hz for 15 h). Using a simple pressure-driven air flow of ∼50 sccm, we confirmed that a ratio of ∼70% of the specific-bounded sites from DNT gas molecules could be regenerated, showing re-usability of the peptide receptor in on-site monitoring for electronic nose applications.
Authors:
 [1] ;  [2] ;  [3] ; ; ; ;  [4] ;  [1]
  1. Department of Electrical Engineering, Kwangwoon University, Seoul 139-701 (Korea, Republic of)
  2. (Korea, Republic of)
  3. Department of Chemical Engineering, Kangwon National University, Kangwon-do 200-701 (Korea, Republic of)
  4. Center for Biomicrosystems, Korea Institute of Science and Technology, Seoul 136-791 (Korea, Republic of)
Publication Date:
OSTI Identifier:
22293062
Resource Type:
Journal Article
Resource Relation:
Journal Name: Applied Physics Letters; Journal Volume: 104; Journal Issue: 8; Other Information: (c) 2014 AIP Publishing LLC; Country of input: International Atomic Energy Agency (IAEA)
Country of Publication:
United States
Language:
English
Subject:
75 CONDENSED MATTER PHYSICS, SUPERCONDUCTIVITY AND SUPERFLUIDITY; AIR FLOW; DIFFUSION; MATERIALS RECOVERY; NANOSTRUCTURES; PEPTIDES; PIEZOELECTRICITY; RECEPTORS; REGENERATION; SENSORS; SURFACES; TOLUENE