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Title: Hybrid radiosity-SP{sub 3} equation based bioluminescence tomography reconstruction for turbid medium with low- and non-scattering regions

Abstract

To provide an ideal solution for a specific problem of gastric cancer detection in which low-scattering regions simultaneously existed with both the non- and high-scattering regions, a novel hybrid radiosity-SP{sub 3} equation based reconstruction algorithm for bioluminescence tomography was proposed in this paper. In the algorithm, the third-order simplified spherical harmonics approximation (SP{sub 3}) was combined with the radiosity equation to describe the bioluminescent light propagation in tissues, which provided acceptable accuracy for the turbid medium with both low- and non-scattering regions. The performance of the algorithm was evaluated with digital mouse based simulations and a gastric cancer-bearing mouse based in situ experiment. Primary results demonstrated the feasibility and superiority of the proposed algorithm for the turbid medium with low- and non-scattering regions.

Authors:
; ; ;  [1]
  1. School of Life Science and Technology, Xidian University, Xi'an, Shaanxi 710071 (China)
Publication Date:
OSTI Identifier:
22271234
Resource Type:
Journal Article
Journal Name:
Journal of Applied Physics
Additional Journal Information:
Journal Volume: 115; Journal Issue: 2; Other Information: (c) 2014 AIP Publishing LLC; Country of input: International Atomic Energy Agency (IAEA); Journal ID: ISSN 0021-8979
Country of Publication:
United States
Language:
English
Subject:
60 APPLIED LIFE SCIENCES; ALGORITHMS; ANIMAL TISSUES; APPROXIMATIONS; BIOLUMINESCENCE; COMPUTERIZED SIMULATION; DIAGNOSIS; DIAGNOSTIC USES; LIGHT TRANSMISSION; MICE; NEOPLASMS; PERFORMANCE; SCATTERING; SPHERICAL HARMONICS; TOMOGRAPHY

Citation Formats

Chen, Xueli, Zhang, Qitan, Yang, Defu, and Liang, Jimin. Hybrid radiosity-SP{sub 3} equation based bioluminescence tomography reconstruction for turbid medium with low- and non-scattering regions. United States: N. p., 2014. Web. doi:10.1063/1.4862166.
Chen, Xueli, Zhang, Qitan, Yang, Defu, & Liang, Jimin. Hybrid radiosity-SP{sub 3} equation based bioluminescence tomography reconstruction for turbid medium with low- and non-scattering regions. United States. https://doi.org/10.1063/1.4862166
Chen, Xueli, Zhang, Qitan, Yang, Defu, and Liang, Jimin. 2014. "Hybrid radiosity-SP{sub 3} equation based bioluminescence tomography reconstruction for turbid medium with low- and non-scattering regions". United States. https://doi.org/10.1063/1.4862166.
@article{osti_22271234,
title = {Hybrid radiosity-SP{sub 3} equation based bioluminescence tomography reconstruction for turbid medium with low- and non-scattering regions},
author = {Chen, Xueli and Zhang, Qitan and Yang, Defu and Liang, Jimin},
abstractNote = {To provide an ideal solution for a specific problem of gastric cancer detection in which low-scattering regions simultaneously existed with both the non- and high-scattering regions, a novel hybrid radiosity-SP{sub 3} equation based reconstruction algorithm for bioluminescence tomography was proposed in this paper. In the algorithm, the third-order simplified spherical harmonics approximation (SP{sub 3}) was combined with the radiosity equation to describe the bioluminescent light propagation in tissues, which provided acceptable accuracy for the turbid medium with both low- and non-scattering regions. The performance of the algorithm was evaluated with digital mouse based simulations and a gastric cancer-bearing mouse based in situ experiment. Primary results demonstrated the feasibility and superiority of the proposed algorithm for the turbid medium with low- and non-scattering regions.},
doi = {10.1063/1.4862166},
url = {https://www.osti.gov/biblio/22271234}, journal = {Journal of Applied Physics},
issn = {0021-8979},
number = 2,
volume = 115,
place = {United States},
year = {Tue Jan 14 00:00:00 EST 2014},
month = {Tue Jan 14 00:00:00 EST 2014}
}