skip to main content

Title: An improved Monte Carlo (MC) dose simulation for charged particle cancer therapy

Heavy-particle therapy such as carbon ion therapy are more popular nowadays because of the nature characteristics of charged particle and almost no side effect to patients. An effective treatment is achieved with high precision of dose calculation, in this research work, Geant4 based Monte Carlo simulation method has been used to calculate the radiation transport and dose distribution. The simulation have the same setting with the treatment room in Heavy Ion Medical Accelerator, HIMAC. The carbon ion beam at the isocentric gantry nozzle for the therapeutic energy of 290 MeV/u was simulated, experimental work was carried out in National Institute of Radiological Sciences, NIRS, Chiba, Japan by using the HIMAC to confirm the accuracy and qualities dose distribution by MC methods. The Geant4 based simulated dose distribution were verified with measurements for Bragg peak and spread out Bragg peak (SOBP) respectively. The verification of results shows that the Bragg peak depth-dose and SOBP distributions in simulation has good agreement with measurements. In overall, the study showed that Geant4 based can be fully applied in the heavy-ion therapy field for simulation, further works need to be carry on to refine and improve the Geant4 MC simulations.
Authors:
 [1] ;  [2] ;  [3] ;  [4]
  1. Advanced Medical and Dental Institute, AMDI, Universiti Sains Malaysia, Penang, Malaysia and School of Medical Sciences, Universiti Sains Malaysia, Kota Bharu (Malaysia)
  2. Advanced Medical and Dental Institute, AMDI, Universiti Sains Malaysia, Penang, Malaysia and Radiology Department, Hospital USM, Kota Bharu (Malaysia)
  3. Advanced Medical and Dental Institute, AMDI, Universiti Sains Malaysia, Penang (Malaysia)
  4. Research Centre of Charged Particle Therapy, National Institute of Radiological Sciences, NIRS, Chiba (Japan)
Publication Date:
OSTI Identifier:
22266093
Resource Type:
Journal Article
Resource Relation:
Journal Name: AIP Conference Proceedings; Journal Volume: 1584; Journal Issue: 1; Conference: iNuSTEC2013: International nuclear science, technology and engineering conference 2013, Kuala Lumpur (Malaysia), 30 Sep - 2 Oct 2013; Other Information: (c) 2014 AIP Publishing LLC; Country of input: International Atomic Energy Agency (IAEA)
Country of Publication:
United States
Language:
English
Subject:
61 RADIATION PROTECTION AND DOSIMETRY; ACCELERATORS; ACCURACY; BRAGG CURVE; CARBON IONS; COMPUTERIZED SIMULATION; DEPTH DOSE DISTRIBUTIONS; DOSES; HEAVY IONS; MONTE CARLO METHOD; NEOPLASMS; PATIENTS; RADIATION TRANSPORT; THERAPY