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Title: Simulation of nanosecond laser-induced thermal dynamics of hollow gold nanoshells for hyperthermia therapy

In this report, we investigate numerically the thermodynamics of hollow gold nanoshell (AuNS) irritated by near-infrared (NIR) light. Simulations are performed for the AuNS in aqueous medium. The nanostructure is illuminated by a nanosecond pulsed laser at plasmonic resonance. The spatiotemporal evolution of the temperature profile inside and outside the AuNS is computed using a numerical framework based on the finite element method (FEM). In particular, we show how the temperature varies with the laser fluence and pulse duration. The aim of this study is to provide a description of the physics of heat release of AuNSs and useful insights for the development of these nanostructures for biomedical applications such as drug delivery, photothermal cancer therapy and optoporation of cells.
Authors:
; ;  [1]
  1. Laser Processing and Plasmonics Laboratory, Department of Engineering Physics, École Polytechnique de Montréal, Montréal, Québec, H3C 3A7 (Canada)
Publication Date:
OSTI Identifier:
22265918
Resource Type:
Journal Article
Resource Relation:
Journal Name: AIP Conference Proceedings; Journal Volume: 1590; Journal Issue: 1; Conference: International conference on electronic, photonic, plasmonic and magnetic properties of nanomaterials, London (Canada), 12-16 Aug 2013; Other Information: (c) 2014 AIP Publishing LLC; Country of input: International Atomic Energy Agency (IAEA)
Country of Publication:
United States
Language:
English
Subject:
77 NANOSCIENCE AND NANOTECHNOLOGY; FINITE ELEMENT METHOD; GOLD; HYPERTHERMIA; LASERS; NANOSTRUCTURES; NEOPLASMS; PULSES; SIMULATION; THERAPY; THERMODYNAMICS