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Title: Antibacterial properties and cytocompatibility of tantalum oxide coatings with different silver content

Tantalum (Ta) oxides and their coatings have been proved to increase their applications in the biomedical fields by improving osseointegration and wear resistance. In this study, Ta oxide coatings containing different proportions of Ag are deposited on SS304 materials. A twin-gun magnetron sputtering system is used to deposit the tantalum oxide-Ag coating. In this study, Staphylococcus aureus, which exhibits physiological commensalism on the human skin, nares, and mucosal and oral areas, is chosen as the model for in vitro antibacterial analyses via a fluorescence staining method using Syto9. The cytocompatibility and adhesive morphology of human skin fibroblast cells (CCD-966SK) on the coatings are also determined by using the microculture tetrazolium assay. This study shows that Ta{sub 2}O{sub 5} and Ta{sub 2}O{sub 5}-Ag coatings with 12.5 at. % of Ag exhibit improved antibacterial effects against S. aureus and have good skin fibroblast cell cellular biocompatibility.
Authors:
 [1] ; ; ;  [2] ;  [3] ;  [4]
  1. School of Dentistry, China Medical University, Taichung 404, Taiwan (China)
  2. Department of Mechanical and Computer-Aided Engineering, National Formosa University, Yunlin 632, Taiwan (China)
  3. School of Medicine, China Medical University, Taichung 404, Taiwan (China)
  4. Division of Oral and Maxillofacial Surgery, China Medical University Hospital, Taichung 404, Taiwan (China)
Publication Date:
OSTI Identifier:
22258643
Resource Type:
Journal Article
Resource Relation:
Journal Name: Journal of Vacuum Science and Technology. A, Vacuum, Surfaces and Films; Journal Volume: 32; Journal Issue: 2; Other Information: (c) 2014 American Vacuum Society; Country of input: International Atomic Energy Agency (IAEA)
Country of Publication:
United States
Language:
English
Subject:
36 MATERIALS SCIENCE; 75 CONDENSED MATTER PHYSICS, SUPERCONDUCTIVITY AND SUPERFLUIDITY; ADHESIVES; COATINGS; FIBROBLASTS; FLUORESCENCE; MAGNETRONS; MORPHOLOGY; SILVER; SPUTTERING; STAPHYLOCOCCUS; TANTALUM; TANTALUM OXIDES; TETRAZOLIUM; WEAR RESISTANCE