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Title: Confocal acoustic radiation force optical coherence elastography using a ring ultrasonic transducer

We designed and developed a confocal acoustic radiation force optical coherence elastography system. A ring ultrasound transducer was used to achieve reflection mode excitation and generate an oscillating acoustic radiation force in order to generate displacements within the tissue, which were detected using the phase-resolved optical coherence elastography method. Both phantom and human tissue tests indicate that this system is able to sense the stiffness difference of samples and quantitatively map the elastic property of materials. Our confocal setup promises a great potential for point by point elastic imaging in vivo and differentiation of diseased tissues from normal tissue.
Authors:
 [1] ;  [2] ;  [1] ; ; ;  [3] ;  [1] ;  [2] ;  [2]
  1. Beckman Laser Institute, University of California, Irvine, 1002 Health Sciences Road East, Irvine, California 92612 (United States)
  2. (United States)
  3. Department of Biomedical Engineering, NIH Ultrasonic Transducer Resource Center, University of Southern California, Los Angeles, California 90089 (United States)
Publication Date:
OSTI Identifier:
22258593
Resource Type:
Journal Article
Resource Relation:
Journal Name: Applied Physics Letters; Journal Volume: 104; Journal Issue: 12; Other Information: (c) 2014 AIP Publishing LLC; Country of input: International Atomic Energy Agency (IAEA)
Country of Publication:
United States
Language:
English
Subject:
62 RADIOLOGY AND NUCLEAR MEDICINE; ACOUSTIC DETECTION; ACOUSTICS; ELASTICITY; PHANTOMS; RINGS; TRANSDUCERS; ULTRASONOGRAPHY