skip to main content

Title: A stochastic model for kinesin bidirectional stepping

In this paper, a hand-over-hand stochastic model for the dynamics of the conventional kinesin is constructed. In the model, both forward and backward motions are taken into consideration. First passage time distributions, average velocities, dwell times, and forward/backward step ratios are investigated based on the model. A good agreement between the results of the model and experimental data is achieved under a variety of external loads.
Authors:
 [1] ;  [2] ;  [1]
  1. School of Physics, Shandong University, Jinan 250100 (China)
  2. (China)
Publication Date:
OSTI Identifier:
22255077
Resource Type:
Journal Article
Resource Relation:
Journal Name: Journal of Chemical Physics; Journal Volume: 140; Journal Issue: 8; Other Information: (c) 2014 AIP Publishing LLC; Country of input: International Atomic Energy Agency (IAEA)
Country of Publication:
United States
Language:
English
Subject:
37 INORGANIC, ORGANIC, PHYSICAL AND ANALYTICAL CHEMISTRY; 60 APPLIED LIFE SCIENCES; EXPERIMENTAL DATA; PROTEINS; SIMULATION