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Title: Development of three-dimension microelectrode array for bioelectric measurement using the liquidmetal-micromolding technique

A method of manufacturing three-dimension microneedle electrode arrays is presented in this paper using the micromolding technology with liquid metal at room temperature, based on the physical property of the Bi-In-Sn liquid metal alloy, being its melting point especially low. Observed under scanning electron microscopy, the needle body of the electrode chip manufactured using this method has a good consistency. Skin penetration test in-vitro indicates that the microneedle electrode can pierce the stratum corneum and cross the high-impedance layer to acquire electrical signals. Electrical impedance and polarization voltage experimental results show that the electrode chips have great electric characteristics and meet the practical application demands.
Authors:
; ;  [1] ; ;  [2] ;  [1] ;  [3]
  1. Department of Biomedical Engineering, School of Medicine, Tsinghua University, Beijing 100084 (China)
  2. College of Information Science and Technology, Beijing University of Chemical Technology, Beijing 100029 (China)
  3. (China)
Publication Date:
OSTI Identifier:
22254144
Resource Type:
Journal Article
Resource Relation:
Journal Name: Applied Physics Letters; Journal Volume: 103; Journal Issue: 19; Other Information: (c) 2013 AIP Publishing LLC; Country of input: International Atomic Energy Agency (IAEA)
Country of Publication:
United States
Language:
English
Subject:
36 MATERIALS SCIENCE; ALLOYS; ELECTRIC POTENTIAL; ELECTRODES; IMPEDANCE; IN VITRO; LIQUID METALS; MANUFACTURING; MELTING POINTS; SCANNING ELECTRON MICROSCOPY; SKIN; TEMPERATURE RANGE 0273-0400 K