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Title: Porous silicon nanoparticles as sensitizers for ultrasonic hyperthermia

Aqueous suspensions of porous silicon nanoparticles (NPs) with average size ∼100 nm and concentration ∼1 g/L undergo significant heating as compared with pure water under therapeutic ultrasonic (US) irradiation with frequencies of 1–2.5 MHz and intensities of 1–20 W/cm{sup 2}. This effect is explained by taking into account the efficient absorption of US energy by NPs. The observed US-induced heating of biodegradable NPs is promising for applications in ultrasonic hyperthermia of tumors.
Authors:
; ; ; ; ;  [1]
  1. Faculty of Physics, M.V. Lomonosov Moscow State University, 119991 Moscow (Russian Federation)
Publication Date:
OSTI Identifier:
22254125
Resource Type:
Journal Article
Resource Relation:
Journal Name: Applied Physics Letters; Journal Volume: 103; Journal Issue: 19; Other Information: (c) 2013 AIP Publishing LLC; Country of input: International Atomic Energy Agency (IAEA)
Country of Publication:
United States
Language:
English
Subject:
77 NANOSCIENCE AND NANOTECHNOLOGY; COMPARATIVE EVALUATIONS; HYPERTHERMIA; IRRADIATION; NANOSTRUCTURES; NEOPLASMS; PARTICLES; POROUS MATERIALS; SILICON; SUSPENSIONS