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Title: Shock-induced termination of reentrant cardiac arrhythmias: Comparing monophasic and biphasic shock protocols

In this article, we compare quantitatively the efficiency of three different protocols commonly used in commercial defibrillators. These are based on monophasic and both symmetric and asymmetric biphasic shocks. A numerical one–dimensional model of cardiac tissue using the bidomain formulation is used in order to test the different protocols. In particular, we performed a total of 4.8 × 10{sup 6} simulations by varying shock waveform, shock energy, initial conditions, and heterogeneity in internal electrical conductivity. Whenever the shock successfully removed the reentrant dynamics in the tissue, we classified the mechanism. The analysis of the numerical data shows that biphasic shocks are significantly more efficient (by about 25%) than the corresponding monophasic ones. We determine that the increase in efficiency of the biphasic shocks can be explained by the higher proportion of newly excited tissue through the mechanism of direct activation.
Authors:
; ;  [1] ; ;  [2] ;  [3] ;  [4] ;  [3] ;  [5]
  1. Department of Physics and Applied Math., University of Navarra, Pamplona (Spain)
  2. School of Physics, Georgia Institute of Technology, Atlanta, Georgia 30332 (United States)
  3. School of Mathematical Sciences, Rochester Institute of Technology, Rochester, New York 14623 (United States)
  4. University of Prince Edward Island, Charlottetown C1A 4P3 (Canada)
  5. (United States)
Publication Date:
OSTI Identifier:
22251909
Resource Type:
Journal Article
Resource Relation:
Journal Name: Chaos (Woodbury, N. Y.); Journal Volume: 23; Journal Issue: 4; Other Information: (c) 2013 AIP Publishing LLC; Country of input: International Atomic Energy Agency (IAEA)
Country of Publication:
United States
Language:
English
Subject:
71 CLASSICAL AND QUANTUM MECHANICS, GENERAL PHYSICS; ANIMAL TISSUES; ASYMMETRY; EFFICIENCY; ELECTRIC CONDUCTIVITY; SIMULATION