Trapping volumetric measurement by multidetector CT in chronic obstructive pulmonary disease: Effect of CT threshold

Wang, Xiaohua; Yuan, Huishu; Duan, Jianghui; Du, Yipeng; Shen, Ning; He, Bei

doi:10.1118/1.4813906

Title: Trapping volumetric measurement by multidetector CT in chronic obstructive pulmonary disease: Effect of CT threshold

Full Record
Other Related Research

Abstract

Purpose: The purpose of this study was to evaluate the effect of various computed tomography (CT) thresholds on trapping volumetric measurements by multidetector CT in chronic obstructive pulmonary disease (COPD).Methods: Twenty-three COPD patients were scanned with a 64-slice CT scanner in both the inspiratory and expiratory phase. CT thresholds of −950 Hu in inspiration and −950 to −890 Hu in expiration were used, after which trapping volumetric measurements were made using computer software. Trapping volume percentage (Vtrap%) under the different CT thresholds in the expiratory phase and below −950 Hu in the inspiratory phase was compared and correlated with lung function.Results: Mean Vtrap% was similar under −930 Hu in the expiratory phase and below −950 Hu in the inspiratory phase, being 13.18 ± 9.66 and 13.95 ± 6.72 (both lungs), respectively; this difference was not significant (P= 0.240). Vtrap% under −950 Hu in the inspiratory phase and below the −950 to −890 Hu threshold in the expiratory phase was moderately negatively correlated with the ratio of forced expiratory volume in one second to forced vital capacity and the measured value of forced expiratory volume in one second as a percentage of the predicted value.Conclusions: Trapping volumetric measurement with multidetector CTmore »« less

Authors:

Wang, Xiaohua; Yuan, Huishu ^[1]; Duan, Jianghui ^[2]; Du, Yipeng; Shen, Ning; He, Bei ^[3]

Department of Radiology, Peking University Third Hospital, Beijing 100191 (China)
Medical School, Peking University, Beijing 100191 (China)
Department of Respiration Internal Medicine, Peking University Third Hospital, Beijing 100191 (China)

Publication Date:: Thu Aug 15 00:00:00 EDT 2013

OSTI Identifier:: 22220527

Resource Type:: Journal Article

Journal Name:: Medical Physics

Additional Journal Information:: Journal Volume: 40; Journal Issue: 8; Other Information: (c) 2013 American Association of Physicists in Medicine; Country of input: International Atomic Energy Agency (IAEA); Journal ID: ISSN 0094-2405

Country of Publication:: United States

Language:: English

Subject:: 62 RADIOLOGY AND NUCLEAR MEDICINE; COMPUTER CODES; COMPUTERIZED TOMOGRAPHY; IMAGE PROCESSING; LUNGS; PATIENTS; RESPIRATORY SYSTEM DISEASES

Citation Formats


                    Wang, Xiaohua, Yuan, Huishu, Duan, Jianghui, Du, Yipeng, Shen, Ning, and He, Bei. Trapping volumetric measurement by multidetector CT in chronic obstructive pulmonary disease: Effect of CT threshold.  United States: N. p., 2013. 
        Web.  doi:10.1118/1.4813906.

Copy to clipboard


                    Wang, Xiaohua, Yuan, Huishu, Duan, Jianghui, Du, Yipeng, Shen, Ning, & He, Bei. Trapping volumetric measurement by multidetector CT in chronic obstructive pulmonary disease: Effect of CT threshold.  United States.  https://doi.org/10.1118/1.4813906

Copy to clipboard


                    Wang, Xiaohua, Yuan, Huishu, Duan, Jianghui, Du, Yipeng, Shen, Ning, and He, Bei. 2013.  
        "Trapping volumetric measurement by multidetector CT in chronic obstructive pulmonary disease: Effect of CT threshold".  United States.  https://doi.org/10.1118/1.4813906.

Copy to clipboard


                    
@article{osti_22220527,

  title        = {Trapping volumetric measurement by multidetector CT in chronic obstructive pulmonary disease: Effect of CT threshold},

  author       = {Wang, Xiaohua and Yuan, Huishu and Duan, Jianghui and Du, Yipeng and Shen, Ning and He, Bei},

  abstractNote = {Purpose: The purpose of this study was to evaluate the effect of various computed tomography (CT) thresholds on trapping volumetric measurements by multidetector CT in chronic obstructive pulmonary disease (COPD).Methods: Twenty-three COPD patients were scanned with a 64-slice CT scanner in both the inspiratory and expiratory phase. CT thresholds of −950 Hu in inspiration and −950 to −890 Hu in expiration were used, after which trapping volumetric measurements were made using computer software. Trapping volume percentage (Vtrap%) under the different CT thresholds in the expiratory phase and below −950 Hu in the inspiratory phase was compared and correlated with lung function.Results: Mean Vtrap% was similar under −930 Hu in the expiratory phase and below −950 Hu in the inspiratory phase, being 13.18 ± 9.66 and 13.95 ± 6.72 (both lungs), respectively; this difference was not significant (P= 0.240). Vtrap% under −950 Hu in the inspiratory phase and below the −950 to −890 Hu threshold in the expiratory phase was moderately negatively correlated with the ratio of forced expiratory volume in one second to forced vital capacity and the measured value of forced expiratory volume in one second as a percentage of the predicted value.Conclusions: Trapping volumetric measurement with multidetector CT is a promising method for the quantification of COPD. It is important to know the effect of various CT thresholds on trapping volumetric measurements.},

  doi          = {10.1118/1.4813906},

  url          = {https://www.osti.gov/biblio/22220527},
  journal      = {Medical Physics},

  issn         = {0094-2405},

  number       = 8,

  volume       = 40,

  place        = {United States},

  year         = {Thu Aug 15 00:00:00 EDT 2013},

  month        = {Thu Aug 15 00:00:00 EDT 2013}

}

Copy to clipboard

Journal Article:

https://doi.org/10.1118/1.4813906

Other availability

Find in Google Scholar

Search WorldCat to find libraries that may hold this journal

Save / Share:

Export Metadata

Save to My Library

Similar records in OSTI.GOV collections:

Investigating the low-dose limits of multidetector CT in lung nodule surveillance

Journal Article Paul, N; Siewerdsen, J; Patsios, D; ... - Medical Physics

The purpose of this study was to evaluate the factors limiting nodule detection in thoracic computed tomography (CT) and to determine whether prior knowledge of nodule size and attenuation, available from a baseline CT study, influences the minimum radiation dose at which nodule surveillance CT scans can be performed while maintaining current levels of nodule detectability. Multiple nodules varying in attenuation (-509 to +110 HU) and diameter (1.6 to 9.5 mm) were layered in random and ordered sequences within 2 lung cylinders made of Rando registered lung material and suspended within a custom-built CT phantom. Multiple CT scans were performedmore »« less
https://doi.org/10.1118/1.2768866
Functional Image-Guided Radiotherapy Planning in Respiratory-Gated Intensity-Modulated Radiotherapy for Lung Cancer Patients With Chronic Obstructive Pulmonary Disease

Journal Article Kimura, Tomoki; Nishibuchi, Ikuno; Murakami, Yuji; ... - International Journal of Radiation Oncology, Biology and Physics

Purpose: To investigate the incorporation of functional lung image-derived low attenuation area (LAA) based on four-dimensional computed tomography (4D-CT) into respiratory-gated intensity-modulated radiotherapy (IMRT) or volumetric modulated arc therapy (VMAT) in treatment planning for lung cancer patients with chronic obstructive pulmonary disease (COPD). Methods and Materials: Eight lung cancer patients with COPD were the subjects of this study. LAA was generated from 4D-CT data sets according to CT values of less than than -860 Hounsfield units (HU) as a threshold. The functional lung image was defined as the area where LAA was excluded from the image of the total lung.more »« less
https://doi.org/10.1016/J.IJROBP.2011.08.016
Pulmonary lobe segmentation based on ridge surface sampling and shape model fitting

Journal Article Kindlmann, Gordon; Okajima, Yuka; Hatabu, Hiroto; ... - Medical Physics

Purpose: Performing lobe-based quantitative analysis of the lung in computed tomography (CT) scans can assist in efforts to better characterize complex diseases such as chronic obstructive pulmonary disease (COPD). While airways and vessels can help to indicate the location of lobe boundaries, segmentations of these structures are not always available, so methods to define the lobes in the absence of these structures are desirable. Methods: The authors present a fully automatic lung lobe segmentation algorithm that is effective in volumetric inspiratory and expiratory computed tomography (CT) datasets. The authors rely on ridge surface image features indicating fissure locations and amore »« less
https://doi.org/10.1118/1.4828782
Pulmonary lobe segmentation based on ridge surface sampling and shape model fitting

Journal Article Kindlmann, Gordon; Okajima, Yuka; Hatabu, Hiroto; ... - Medical Physics

Purpose: Performing lobe-based quantitative analysis of the lung in computed tomography (CT) scans can assist in efforts to better characterize complex diseases such as chronic obstructive pulmonary disease (COPD). While airways and vessels can help to indicate the location of lobe boundaries, segmentations of these structures are not always available, so methods to define the lobes in the absence of these structures are desirable. Methods: The authors present a fully automatic lung lobe segmentation algorithm that is effective in volumetric inspiratory and expiratory computed tomography (CT) datasets. The authors rely on ridge surface image features indicating fissure locations and amore »« less
https://doi.org/10.1118/1.4828782
SU-E-T-217: Intrinsic Respiratory Gating in Small Animal CT

Journal Article Liu, Y; Smith, M; Mistry, N - Medical Physics

Purpose: Preclinical animal models of lung cancer can provide a controlled test-bed for testing dose escalation or function-based-treatment-planning studies. However, to extract lung function, i.e. ventilation, one needs to be able to image the lung at different phases of ventilation (in-hale / ex-hale). Most respiratory-gated imaging using micro-CT involves using an external ventilator and surgical intervention limiting the utility in longitudinal studies. A new intrinsic respiratory retrospective gating method was developed and tested in mice. Methods: A fixed region of interest (ROI) that covers the diaphragm was selected on all projection images to estimate the mean intensity (M). The meanmore »« less
https://doi.org/10.1118/1.4888547

Similar Records