skip to main content

Title: Single shot cell irradiations with laser-driven protons

Ion beams are relevant for radiobiological studies in basic research and for application in tumor therapy. Here we present a method to generate nanosecond proton bunches with single shot doses of up to 7 Gray by a tabletop high-power laser. Although in their infancy, laser-ion accelerators allow studying fast radiobiological processes at small-scale laboratories as exemplarily demonstrated by measurements of the relative biological effectiveness of protons in human tumor cells.
Authors:
; ; ;  [1] ; ; ; ;  [2] ; ; ;  [3] ; ;  [4]
  1. Department of Radiation Oncology, Klinikum rechts der Isar, Technische Universität München (Germany)
  2. Physics Department, Ludwig-Maximilians-Universität München (Germany)
  3. Max Planck Institute of Quantum Optics, Garching (Germany)
  4. Department of Radiation Oncology, Ludwig-Maximilians-Universität München (Germany)
Publication Date:
OSTI Identifier:
22218282
Resource Type:
Journal Article
Resource Relation:
Journal Name: AIP Conference Proceedings; Journal Volume: 1546; Journal Issue: 1; Conference: 2. ELIMED workshop and panel, Catania (Italy), 18-19 Oct 2012; Other Information: (c) 2013 AIP Publishing LLC; Country of input: International Atomic Energy Agency (IAEA)
Country of Publication:
United States
Language:
English
Subject:
43 PARTICLE ACCELERATORS; 62 RADIOLOGY AND NUCLEAR MEDICINE; ACCELERATORS; BEAM BUNCHING; BEAM PRODUCTION; BIOLOGICAL RADIATION EFFECTS; HUMAN POPULATIONS; ION BEAMS; LASER-PRODUCED PLASMA; LASERS; NEOPLASMS; PROTON BEAMS; PROTONS; RADIATION DOSE UNITS; RADIOTHERAPY; RBE; TUMOR CELLS