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Title: Y90-Radioembolization of Lung Metastases via the Bronchial Artery: A Report of 2 Cases

We report successful Y90-radioembolization of the lung applying Y90-resin microspheres via the bronchial artery in two patients with diffuse colorectal and renal cancer metastases, respectively. The deposition of radioactive Y90-resin-microspheres was technically feasible and resulted in a reasonable absorbed dose in the tumors. However, open questions remain regarding dosimetry and safe dose exposure to the lung. The technique warrants thorough investigation before clinical use. A Phase I trial to evaluate safety and preliminary efficacy is under preparation.
Authors:
; ;  [1]
  1. Universitaetsklinikum Magdeburg AoeR, Klinik fuer Radiologie und Nuklearmedizin (Germany)
Publication Date:
OSTI Identifier:
22207958
Resource Type:
Journal Article
Resource Relation:
Journal Name: Cardiovascular and Interventional Radiology; Journal Volume: 36; Journal Issue: 6; Other Information: Copyright (c) 2013 Springer Science+Business Media New York and the Cardiovascular and Interventional Radiological Society of Europe (CIRSE); http://www.springer-ny.com; Country of input: International Atomic Energy Agency (IAEA)
Country of Publication:
United States
Language:
English
Subject:
62 RADIOLOGY AND NUCLEAR MEDICINE; ABSORBED RADIATION DOSES; ARTERIES; DOSIMETRY; KIDNEYS; LUNGS; METASTASES; MICROSPHERES; NEOPLASMS; PATIENTS; YTTRIUM 90 RADIOEMBOLIZATION