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Title: Online determination of biophysical parameters of mucous membranes of a human body

We have developed a method for online determination of biophysical parameters of mucous membranes (MMs) of a human body (transport scattering coefficient, scattering anisotropy factor, haemoglobin concentration, degrees of blood oxygenation, average diameter of capillaries with blood) from measurements of spectral and spatial characteristics of diffuse reflection. The method is based on regression relationships between linearly independent components of the measured light signals and the unknown parameters of MMs, obtained by simulation of the radiation transfer in the MM under conditions of its general variability. We have proposed and justified the calibration-free fibre-optic method for determining the concentration of haemoglobin in MMs by measuring the light signals diffusely reflected by the tissue in four spectral regions at two different distances from the illumination spot. We have selected the optimal wavelengths of optical probing for the implementation of the method. (laser applications in biology and medicine)
Authors:
;  [1]
  1. Belarusian State University, Minsk (Belarus)
Publication Date:
OSTI Identifier:
22156613
Resource Type:
Journal Article
Resource Relation:
Journal Name: Quantum Electronics (Woodbury, N.Y.); Journal Volume: 43; Journal Issue: 7; Other Information: Country of input: International Atomic Energy Agency (IAEA)
Country of Publication:
United States
Language:
English
Subject:
71 CLASSICAL AND QUANTUM MECHANICS, GENERAL PHYSICS; 62 RADIOLOGY AND NUCLEAR MEDICINE; ANIMAL TISSUES; ANISOTROPY; BLOOD; CALIBRATION; CAPILLARIES; CONCENTRATION RATIO; FIBER OPTICS; HEMOGLOBIN; LASERS; MEDICINE; MUCOUS MEMBRANES; RADIATION TRANSPORT; SCATTERING; SIGNALS; SIMULATION; VISIBLE RADIATION