skip to main content

SciTech ConnectSciTech Connect

Title: Simulation of a broadband nano-biosensor based on an onion-like quantum dot-quantum well structure

The fluorescence resonance energy transfer is studied between modified quantum-dots and quantum-wells used as a donor and an acceptor. Because of the unique properties of quantum dots, including diverse surface modification flexibility, bio-compatibility, high quantum yields and wide absorption, their use as nano-biosensors and bio-markers used in diagnosis of cancer is suggested. The fluorescence resonance energy transfer is simulated in a quantum dot-quantum well system, where the energy can flow from donor to acceptor. If the energy transfer can be either turned on or off by a specific interaction, such as interaction with any dyes, a molecular binding event or a cleavage reaction, a sensor can be designed (under assumption that the healthy cells have a known effect or unyielding effect on output parameters while cancerous cells, due to their pandemic optical properties, can impact the fluorescence resonance energy transfer parameters). The developed nano-biosensor can operate in a wide range of wavelengths (310 - 760 nm). (laser applications in biology and medicine)
Authors:
; ;
Publication Date:
OSTI Identifier:
22156611
Resource Type:
Journal Article
Resource Relation:
Journal Name: Quantum Electronics (Woodbury, N.Y.); Journal Volume: 43; Journal Issue: 7; Other Information: Country of input: International Atomic Energy Agency (IAEA)
Country of Publication:
United States
Language:
English
Subject:
71 CLASSICAL AND QUANTUM MECHANICS, GENERAL PHYSICS; 62 RADIOLOGY AND NUCLEAR MEDICINE; DIAGNOSIS; DYES; ENERGY TRANSFER; FLUORESCENCE; INTERACTIONS; MEDICINE; OPTICAL PROPERTIES; QUANTUM DOTS; QUANTUM WELLS; RESONANCE; SIMULATION