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Title: MR-CT registration using a Ni-Ti prostate stent in image-guided radiotherapy of prostate cancer

Journal Article · · Medical Physics
DOI:https://doi.org/10.1118/1.4807087· OSTI ID:22121028
;  [1];  [2]
  1. Department of Health Science and Technology, Aalborg University, Aalborg 9220 (Denmark)
  2. Department of Medical Physics, Oncology, Aalborg Hospital, Aalborg 9100 (Denmark)

Purpose: In image-guided radiotherapy of prostate cancer defining the clinical target volume often relies on magnetic resonance (MR). The task of transferring the clinical target volume from MR to standard planning computed tomography (CT) is not trivial due to prostate mobility. In this paper, an automatic local registration approach is proposed based on a newly developed removable Ni-Ti prostate stent.Methods: The registration uses the voxel similarity measure mutual information in a two-step approach where the pelvic bones are used to establish an initial registration for the local registration.Results: In a phantom study, the accuracy was measured to 0.97 mm and visual inspection showed accurate registration of all 30 data sets. The consistency of the registration was examined where translation and rotation displacements yield a rotation error of 0.41 Degree-Sign {+-} 0.45 Degree-Sign and a translation error of 1.67 {+-} 2.24 mm.Conclusions: This study demonstrated the feasibility for an automatic local MR-CT registration using the prostate stent.

OSTI ID:
22121028
Journal Information:
Medical Physics, Vol. 40, Issue 6; Other Information: (c) 2013 American Association of Physicists in Medicine; Country of input: International Atomic Energy Agency (IAEA); ISSN 0094-2405
Country of Publication:
United States
Language:
English