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Title: Spatially resolved measurement of high doses in microbeam radiation therapy using samarium doped fluorophosphate glasses

The measurement of spatially resolved high doses in microbeam radiation therapy has always been a challenging task, where a combination of high dose response and high spatial resolution (microns) is required for synchrotron radiation peaked around 50 keV. The x-ray induced Sm{sup 3+}{yields} Sm{sup 2+} valence conversion in Sm{sup 3+} doped fluorophosphates glasses has been tested for use in x-ray dosimetry for microbeam radiation therapy. The conversion efficiency depends almost linearly on the dose of irradiation up to {approx}5 Gy and saturates at doses exceeding {approx}80 Gy. The conversion shows strong correlation with x-ray induced absorbance of the glass which is related to the formation of phosphorus-oxygen hole centers. When irradiated through a microslit collimator, a good spatial resolution and high ''peak-to-valley'' contrast have been observed by means of confocal photoluminescence microscopy.
Authors:
; ; ;  [1] ; ;  [2] ; ;  [3] ;  [4]
  1. Department of Electrical and Computer Engineering, University of Saskatchewan, Saskatoon, SK S7N 5A9 (Canada)
  2. School of Chemical and Physical Sciences and MacDiarmid Institute, Victoria University of Wellington, Kelburn Parade (New Zealand)
  3. Canadian Light Source Inc., University of Saskatchewan, Saskatoon, SK S7N 0X4 (Canada)
  4. Department of Anatomy and Cell Biology, University of Saskatchewan, Saskatoon, SK S7N 5E5 (Canada)
Publication Date:
OSTI Identifier:
22027742
Resource Type:
Journal Article
Resource Relation:
Journal Name: Applied Physics Letters; Journal Volume: 99; Journal Issue: 12; Other Information: (c) 2011 American Institute of Physics; Country of input: International Atomic Energy Agency (IAEA)
Country of Publication:
United States
Language:
English
Subject:
36 MATERIALS SCIENCE; 62 RADIOLOGY AND NUCLEAR MEDICINE; 61 RADIATION PROTECTION AND DOSIMETRY; CORRELATIONS; DOPED MATERIALS; IRRADIATION; OPTICAL MICROSCOPY; PHOSPHATE GLASS; PHOTOLUMINESCENCE; RADIATION DOSES; RADIOTHERAPY; SAMARIUM; SAMARIUM IONS; SPATIAL RESOLUTION; SYNCHROTRON RADIATION; X RADIATION; X-RAY DOSIMETRY