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Title: Application of synchrotron radiation computed microtomography for quantification of bone microstructure in human and rat bones

Abstract

This work aims to evaluate histomorphometric quantification by synchrotron radiation computed microto-mography in bones of human and rat specimens. Bones specimens are classified as normal and pathological (for human samples) and irradiated and non-irradiated samples (for rat ones). Human bones are specimens which were affected by some injury, or not. Rat bones are specimens which were irradiated, simulating radiotherapy procedures, or not. Images were obtained on SYRMEP beamline at the Elettra Synchrotron Laboratory in Trieste, Italy. The system generated 14 {mu}m tomographic images. The quantification of bone structures were performed directly by the 3D rendered images using a home-made software. Resolution yielded was excellent what facilitate quantification of bone microstructures.

Authors:
; ; ; ; ; ;  [1]
  1. Nuclear Instrumentation Laboratory / COPPE / UFRJ, P.O. Box 68509, 21945-970, Rio de Janeiro (Brazil)
Publication Date:
OSTI Identifier:
22004044
Resource Type:
Journal Article
Journal Name:
AIP Conference Proceedings
Additional Journal Information:
Journal Volume: 1437; Journal Issue: 1; Conference: 21. international congress on X-ray optics and microanalysis, Campinas (Brazil), 5-9 Sep 2011; Other Information: (c) 2012 American Institute of Physics; Country of input: International Atomic Energy Agency (IAEA); Journal ID: ISSN 0094-243X
Country of Publication:
United States
Language:
English
Subject:
62 RADIOLOGY AND NUCLEAR MEDICINE; 60 APPLIED LIFE SCIENCES; COMPUTER CODES; COMPUTER GRAPHICS; COMPUTERIZED TOMOGRAPHY; HUMAN POPULATIONS; IMAGE PROCESSING; IMAGES; INJURIES; MICROSTRUCTURE; RADIOTHERAPY; RATS; RESOLUTION; SKELETON; SYNCHROTRON RADIATION

Citation Formats

Parreiras Nogueira, Liebert, Barroso, Regina Cely, Pereira de Almeida, Andre, Braz, Delson, Almeida, Carlos Eduardo de, Borba de Andrade, Cherley, Tromba, Giuliana, Physics Institute / State University of Rio de Janeiro, 20550-900, Rio de Janeiro, Nuclear Instrumentation Laboratory / COPPE / UFRJ, P.O. Box 68509, 21945-970, Rio de Janeiro, Laboratory of Radiological Sciences / State University of Rio de Janeiro, Rio de Janeiro, and Sincrotrone Trieste SCpA, Strada Statale S.S. 14 km 163.5, 34012 Basovizza, Trieste. Application of synchrotron radiation computed microtomography for quantification of bone microstructure in human and rat bones. United States: N. p., 2012. Web. doi:10.1063/1.3703340.
Parreiras Nogueira, Liebert, Barroso, Regina Cely, Pereira de Almeida, Andre, Braz, Delson, Almeida, Carlos Eduardo de, Borba de Andrade, Cherley, Tromba, Giuliana, Physics Institute / State University of Rio de Janeiro, 20550-900, Rio de Janeiro, Nuclear Instrumentation Laboratory / COPPE / UFRJ, P.O. Box 68509, 21945-970, Rio de Janeiro, Laboratory of Radiological Sciences / State University of Rio de Janeiro, Rio de Janeiro, & Sincrotrone Trieste SCpA, Strada Statale S.S. 14 km 163.5, 34012 Basovizza, Trieste. Application of synchrotron radiation computed microtomography for quantification of bone microstructure in human and rat bones. United States. https://doi.org/10.1063/1.3703340
Parreiras Nogueira, Liebert, Barroso, Regina Cely, Pereira de Almeida, Andre, Braz, Delson, Almeida, Carlos Eduardo de, Borba de Andrade, Cherley, Tromba, Giuliana, Physics Institute / State University of Rio de Janeiro, 20550-900, Rio de Janeiro, Nuclear Instrumentation Laboratory / COPPE / UFRJ, P.O. Box 68509, 21945-970, Rio de Janeiro, Laboratory of Radiological Sciences / State University of Rio de Janeiro, Rio de Janeiro, and Sincrotrone Trieste SCpA, Strada Statale S.S. 14 km 163.5, 34012 Basovizza, Trieste. 2012. "Application of synchrotron radiation computed microtomography for quantification of bone microstructure in human and rat bones". United States. https://doi.org/10.1063/1.3703340.
@article{osti_22004044,
title = {Application of synchrotron radiation computed microtomography for quantification of bone microstructure in human and rat bones},
author = {Parreiras Nogueira, Liebert and Barroso, Regina Cely and Pereira de Almeida, Andre and Braz, Delson and Almeida, Carlos Eduardo de and Borba de Andrade, Cherley and Tromba, Giuliana and Physics Institute / State University of Rio de Janeiro, 20550-900, Rio de Janeiro and Nuclear Instrumentation Laboratory / COPPE / UFRJ, P.O. Box 68509, 21945-970, Rio de Janeiro and Laboratory of Radiological Sciences / State University of Rio de Janeiro, Rio de Janeiro and Sincrotrone Trieste SCpA, Strada Statale S.S. 14 km 163.5, 34012 Basovizza, Trieste},
abstractNote = {This work aims to evaluate histomorphometric quantification by synchrotron radiation computed microto-mography in bones of human and rat specimens. Bones specimens are classified as normal and pathological (for human samples) and irradiated and non-irradiated samples (for rat ones). Human bones are specimens which were affected by some injury, or not. Rat bones are specimens which were irradiated, simulating radiotherapy procedures, or not. Images were obtained on SYRMEP beamline at the Elettra Synchrotron Laboratory in Trieste, Italy. The system generated 14 {mu}m tomographic images. The quantification of bone structures were performed directly by the 3D rendered images using a home-made software. Resolution yielded was excellent what facilitate quantification of bone microstructures.},
doi = {10.1063/1.3703340},
url = {https://www.osti.gov/biblio/22004044}, journal = {AIP Conference Proceedings},
issn = {0094-243X},
number = 1,
volume = 1437,
place = {United States},
year = {Thu May 17 00:00:00 EDT 2012},
month = {Thu May 17 00:00:00 EDT 2012}
}