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Title: Successful Antibiotic Treatment of Severe Staphylococcal Infection of a Long Stent Graft in the Superficial Femoral Artery with Graft Preservation in the Long Term

Introduction: Bacterial infection of endovascular stent grafts is a serious condition, regularly leading to graft replacement by open bypass surgery.Case ReportWe describe the case of a staphylococcal infection of a 150-mm covered stent graft (Gore Viabahn), placed in the superficial femoral artery. Stent graft infection was successfully treated by oral administration of penicillinase-resistant flucloxacillin and the lipopeptide daptomycin with complete graft preservation, not requiring surgical treatment. During 1-year follow-up, the graft infection did not reappear. However, the patient developed restenosis at the proximal margin of the stent with recurrence of mild claudication, so far treated conservatively. Conclusion: With the increased use of covered stent grafts in the peripheral vasculature, the frequency of graft infection will increase. We demonstrate that with newly developed antibiotics, it is possible to treat this severe complication conservatively, with complete graft preservation and without the need for bypass surgery in selected cases.
Authors:
 [1] ;  [2] ; ;  [1] ; ;  [2]
  1. Clinical Center of the Ludwig-Maximilians-University of Munich, Department for Clinical Radiology (Germany)
  2. Clinical Center of the Ludwig-Maximilians-University of Munich, Division of Vascular Medicine, Medical Policlinic (Germany)
Publication Date:
OSTI Identifier:
21608700
Resource Type:
Journal Article
Resource Relation:
Journal Name: Cardiovascular and Interventional Radiology; Journal Volume: 34; Journal Issue: 3; Conference: CIRSE 2011: Annual meeting of the Cardiovascular and Interventional Radiological Society of Europe, Munich (Germany), 10-14 Sep 2011; Other Information: DOI: 10.1007/s00270-010-0040-7; Copyright (c) 2011 Springer Science+Business Media, LLC and the Cardiovascular and Interventional Radiological Society of Europe (CIRSE); Country of input: International Atomic Energy Agency (IAEA)
Country of Publication:
United States
Language:
English
Subject:
62 RADIOLOGY AND NUCLEAR MEDICINE; ANTIBIOTICS; ARTERIES; BYPASSES; GRAFTS; ORAL ADMINISTRATION; PATIENTS; SURGERY ANTI-INFECTIVE AGENTS; BLOOD VESSELS; BODY; CARDIOVASCULAR SYSTEM; DRUGS; INTAKE; MEDICINE; ORGANIC COMPOUNDS; ORGANS; TRANSPLANTS