Initial Experience With Volumetric IMRT (RapidArc) for Intracranial Stereotactic Radiosurgery
- Department of Radiation Oncology, University of Massachusetts Medical School, Worcester, MA (United States)
Purpose: Initial experience with delivering frameless stereotactic radiotherapy (SRT) using volumetric intensity-modulated radiation therapy (IMRT) delivered with RapidArc is presented. Methods and Materials: Treatment details for 12 patients (14 targets) with a mean clinical target volume (CTV) of 12.8 {+-} 4.0 cm{sup 3} were examined. Dosimetric indices for conformality, homogeneity, and dose gradient were calculated and compared with published results for other frameless, intracranial SRT techniques, including CyberKnife, TomoTherapy, and static-beam IMRT. Statistics on setup and treatment times and per patient dose validations were examined. Results: Dose indices compared favorably with other techniques. Mean conformality, gradient, and homogeneity index values were 1.10 {+-} 0.11, 64.9 {+-} 14.1, 1.083 {+-} 0.026, respectively. Median treatment times were 4.8 {+-} 1.7 min. Conclusion: SRT using volumetric IMRT is a viable alternative to other techniques and enables short treatment times. This is anticipated to have a positive impact on radiobiological effect and for facilitating wider use of SRT.
- OSTI ID:
- 21491515
- Journal Information:
- International Journal of Radiation Oncology, Biology and Physics, Vol. 78, Issue 5; Other Information: DOI: 10.1016/j.ijrobp.2009.10.005; PII: S0360-3016(09)03338-0; Copyright (c) 2010 Elsevier Science B.V., Amsterdam, The Netherlands, All rights reserved.; ISSN 0360-3016
- Country of Publication:
- United States
- Language:
- English
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