Long Range Correlation of Hydrophilicity and Flexibility Along the Hemoglobin Chain

Journal Article · Wed Aug 04 00:00:00 EDT 2010 · AIP Conference Proceedings

DOI:https://doi.org/10.1063/1.3482227· OSTI ID:21460005

Craciun, D ^[1]; Isvoran, A ^[2]; Avram, N M ^[3]

---

1. West Univ. of Timisoara, Teacher Training Dept, Blvd. V. Parvan 4, Timisoara, 300223 (Romania)
2. West Univ. of Timisoara, Department of Chemistry, Str. Pestalozzi 16, Timisoara, 300115 (Romania)
3. West University of Timisoara, Department of Physics, Blvd. V. Parvan 4, Timisoara, 300223 (Romania)

Within this study, we reveal the long range correlation concerning hydrophilicity and flexibility along sequences of hemoglobins belonging to different organisms and we compare them with the long range correlations properties obtained for other protein families. For all hemoglobins considered, we investigate two discrete spatial series: the hydrophilicity and flexibility respectively. We apply the nonlinear analysis methods to analyze the two spatial series by calculating the spectral coefficient {beta}, the scaling exponent {alpha} and Hurst exponent H. The obtained values for the mentioned coefficients suggest long range correlation within the analyzed sequences of hemoglobins in good agreement with those obtained for the calcium binding proteins and hydrolases.

• OSTI ID: 21460005
• Journal Information: AIP Conference Proceedings, Vol. 1262, Issue 1; Conference: TIM-09: Physics conference, Timisoara (Romania), 27-28 Nov 2010; Other Information: DOI: 10.1063/1.3482227; (c) 2010 American Institute of Physics; ISSN 0094-243X
• Country of Publication: United States
• Language: English

Related Subjects

60 APPLIED LIFE SCIENCES
BLOOD
CALCIUM
COMPARATIVE EVALUATIONS
CORRELATIONS
FLEXIBILITY
FLUCTUATIONS
HEMOGLOBIN
HYDROLASES
NONLINEAR PROBLEMS
ALKALINE EARTH METALS
BIOLOGICAL MATERIALS
BODY FLUIDS
CARBOXYLIC ACIDS
ELEMENTS
ENZYMES
EVALUATION
GLOBINS
HETEROCYCLIC ACIDS
HETEROCYCLIC COMPOUNDS
MATERIALS
MECHANICAL PROPERTIES
METALS
ORGANIC ACIDS
ORGANIC COMPOUNDS
ORGANIC NITROGEN COMPOUNDS
PIGMENTS
PORPHYRINS
PROTEINS
TENSILE PROPERTIES
VARIATIONS