Fabrication of a novel poly(3-hydroxyoctanoate)/ nanoscale bioactive glass composite film with potential as a multifunctional wound dressing

Journal Article · Wed Jun 02 00:00:00 EDT 2010 · AIP Conference Proceedings

DOI:https://doi.org/10.1063/1.3455552· OSTI ID:21377982

Rai, Ranjana; Keshavarz, Tajalli; Roy, Ipsita ^[1]; Boccaccini, Aldo R ^[2]; Knowles, Jonathan C; Salih, Vehid; Mordon, Nicola ^[3]; Locke, Ian C; Gordge, Michael P ^[4]; McCormick, Aine ^[5]

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1. Department of Molecular and Applied Biosciences, University of Westminster, London W1W 6UW (United Kingdom)
2. Department of Materials, Imperial College London, London SW7 2AZ (United Kingdom); Department of Materials Science and Engineering, University of Erlangen, Nuremberg Cauestr. 6. 91058 (Germany)
3. Division of Biomterials and Tissue Engineering, UCL Eastman Dental Institute, London WCIX 8LD (United Kingdom)
4. Department of Biomedical Sciences, School of Lifesciences, University of Westminster, London W1W 6UW (United Kingdom)
5. Haemophilia Reference Centre, St. Thomas' Hospital, Lambeth Palace Road, London SE1 7EH (United Kingdom)

Fabrication of a composite scaffold of nanobioglass (n-BG) 45S5 and poly(3-hydroxyocatnoate), P(3HO) was studied for the first time with the aim of developing a novel, multifunctional wound dressing. The incorporation of n-BG accelerated blood clotting time and its incorporation in the polymer matrix enhanced the wettability, surface roughness and bio-compatibility of the scaffold.

• OSTI ID: 21377982
• Journal Information: AIP Conference Proceedings, Vol. 1255, Issue 1; Conference: 5. international conference on times of polymers (TOP) and composites, Ischia (Italy), 20-23 Jun 2010; Other Information: DOI: 10.1063/1.3455552; (c) 2010 American Institute of Physics; ISSN 0094-243X
• Country of Publication: United States
• Language: English

Related Subjects

77 NANOSCIENCE AND NANOTECHNOLOGY
BIOPHYSICS
BLOOD COAGULATION
COMPOSITE MATERIALS
FABRICATION
FILMS
GLASS
NANOSTRUCTURES
POLYMERS
ROUGHNESS
WETTABILITY
WOUNDS
DISEASES
INJURIES
MATERIALS
PHYSICS
SURFACE PROPERTIES