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Title: Clinical Experience With Image-Guided Radiotherapy in an Accelerated Partial Breast Intensity-Modulated Radiotherapy Protocol

Abstract

Purpose: To explore the feasibility of fiducial markers for the use of image-guided radiotherapy (IGRT) in an accelerated partial breast intensity modulated radiotherapy protocol. Methods and Materials: Nineteen patients consented to an institutional review board approved protocol of accelerated partial breast intensity-modulated radiotherapy with fiducial marker placement and treatment with IGRT. Patients (1 patient with bilateral breast cancer; 20 total breasts) underwent ultrasound guided implantation of three 1.2- x 3-mm gold markers placed around the surgical cavity. For each patient, table shifts (inferior/superior, right/left lateral, and anterior/posterior) and minimum, maximum, mean error with standard deviation were recorded for each of the 10 BID treatments. The dose contribution of daily orthogonal films was also examined. Results: All IGRT patients underwent successful marker placement. In all, 200 IGRT treatment sessions were performed. The average vector displacement was 4 mm (range, 2-7 mm). The average superior/inferior shift was 2 mm (range, 0-5 mm), the average lateral shift was 2 mm (range, 1-4 mm), and the average anterior/posterior shift was 3 mm (range, 1 5 mm). Conclusions: This study shows that the use of IGRT can be successfully used in an accelerated partial breast intensity-modulated radiotherapy protocol. The authors believe that this technique hasmore » increased daily treatment accuracy and permitted reduction in the margin added to the clinical target volume to form the planning target volume.« less

Authors:
; ;  [1]; ;  [2];  [3]; ;  [4];  [1]
  1. Rocky Mountain Cancer Centers, Littleton, CO (United States)
  2. Arapahoe Surgical Associates, Littleton, CO (United States)
  3. Sally Jobe Diagnostic Breast Center, Greenwood Village, CO (United States)
  4. Rocky Mountain Cancer Centers, Rose Hospital, Denver, CO (United States)
Publication Date:
OSTI Identifier:
21372070
Resource Type:
Journal Article
Journal Name:
International Journal of Radiation Oncology, Biology and Physics
Additional Journal Information:
Journal Volume: 76; Journal Issue: 2; Other Information: DOI: 10.1016/j.ijrobp.2009.02.001; PII: S0360-3016(09)00185-0; Copyright (c) 2010 Elsevier Science B.V., Amsterdam, The Netherlands, All rights reserved.; Journal ID: ISSN 0360-3016
Country of Publication:
United States
Language:
English
Subject:
62 RADIOLOGY AND NUCLEAR MEDICINE; MAMMARY GLANDS; RADIATION DOSES; RADIOTHERAPY; BODY; DOSES; GLANDS; MEDICINE; NUCLEAR MEDICINE; ORGANS; RADIOLOGY; THERAPY

Citation Formats

Leonard, Charles E., E-mail: charles.leonard@usoncology.co, Tallhamer, Michael M.S., Johnson, Tim, Hunter, Kari C.M.D., Howell, Kathryn, Kercher, Jane, Widener, Jodi, Kaske, Terese, Paul, Devchand, Sedlacek, Scot, and Carter, Dennis L. Clinical Experience With Image-Guided Radiotherapy in an Accelerated Partial Breast Intensity-Modulated Radiotherapy Protocol. United States: N. p., 2010. Web. doi:10.1016/j.ijrobp.2009.02.001.
Leonard, Charles E., E-mail: charles.leonard@usoncology.co, Tallhamer, Michael M.S., Johnson, Tim, Hunter, Kari C.M.D., Howell, Kathryn, Kercher, Jane, Widener, Jodi, Kaske, Terese, Paul, Devchand, Sedlacek, Scot, & Carter, Dennis L. Clinical Experience With Image-Guided Radiotherapy in an Accelerated Partial Breast Intensity-Modulated Radiotherapy Protocol. United States. https://doi.org/10.1016/j.ijrobp.2009.02.001
Leonard, Charles E., E-mail: charles.leonard@usoncology.co, Tallhamer, Michael M.S., Johnson, Tim, Hunter, Kari C.M.D., Howell, Kathryn, Kercher, Jane, Widener, Jodi, Kaske, Terese, Paul, Devchand, Sedlacek, Scot, and Carter, Dennis L. 2010. "Clinical Experience With Image-Guided Radiotherapy in an Accelerated Partial Breast Intensity-Modulated Radiotherapy Protocol". United States. https://doi.org/10.1016/j.ijrobp.2009.02.001.
@article{osti_21372070,
title = {Clinical Experience With Image-Guided Radiotherapy in an Accelerated Partial Breast Intensity-Modulated Radiotherapy Protocol},
author = {Leonard, Charles E., E-mail: charles.leonard@usoncology.co and Tallhamer, Michael M.S. and Johnson, Tim and Hunter, Kari C.M.D. and Howell, Kathryn and Kercher, Jane and Widener, Jodi and Kaske, Terese and Paul, Devchand and Sedlacek, Scot and Carter, Dennis L},
abstractNote = {Purpose: To explore the feasibility of fiducial markers for the use of image-guided radiotherapy (IGRT) in an accelerated partial breast intensity modulated radiotherapy protocol. Methods and Materials: Nineteen patients consented to an institutional review board approved protocol of accelerated partial breast intensity-modulated radiotherapy with fiducial marker placement and treatment with IGRT. Patients (1 patient with bilateral breast cancer; 20 total breasts) underwent ultrasound guided implantation of three 1.2- x 3-mm gold markers placed around the surgical cavity. For each patient, table shifts (inferior/superior, right/left lateral, and anterior/posterior) and minimum, maximum, mean error with standard deviation were recorded for each of the 10 BID treatments. The dose contribution of daily orthogonal films was also examined. Results: All IGRT patients underwent successful marker placement. In all, 200 IGRT treatment sessions were performed. The average vector displacement was 4 mm (range, 2-7 mm). The average superior/inferior shift was 2 mm (range, 0-5 mm), the average lateral shift was 2 mm (range, 1-4 mm), and the average anterior/posterior shift was 3 mm (range, 1 5 mm). Conclusions: This study shows that the use of IGRT can be successfully used in an accelerated partial breast intensity-modulated radiotherapy protocol. The authors believe that this technique has increased daily treatment accuracy and permitted reduction in the margin added to the clinical target volume to form the planning target volume.},
doi = {10.1016/j.ijrobp.2009.02.001},
url = {https://www.osti.gov/biblio/21372070}, journal = {International Journal of Radiation Oncology, Biology and Physics},
issn = {0360-3016},
number = 2,
volume = 76,
place = {United States},
year = {Mon Feb 01 00:00:00 EST 2010},
month = {Mon Feb 01 00:00:00 EST 2010}
}