Characteristics of Gadolinium Oxide Nanoparticles Using Terahertz Spectroscopy
- Department of Physics, University of Seoul, Seoul (Korea, Republic of)
- Brain Korea 21 Project for Medical Science, Yonsei University, Seoul (Korea, Republic of)
- Department of Chemistry, Korea University, Seoul (Korea, Republic of)
The penetration property of the terahertz electromagnetic (THz) wave is relevant to its use. We used the THz wave spectroscopy system which easily penetrates some materials that do not contain water, e.g., plastic and ceramics. The system has been developed for several purposes, including measuring the properties of semiconductors and bio-materials, and detecting plastic bombs and ceramic knives at airports. It is also used for medical imaging systems, such as magnetic resonance imaging (MRI), at some research institutes. It can show not only the difference in amplitude, but also the difference of the phase of each point of sample. MRI technology usually uses contrast agents to enhance the quality of the image. Gadolinium diethylenetriamine pentaacetic acid (Gd-DTPA), made with a heavy metal ion, is commonly used as a clinical MRI contrast agent. Gadolinium oxide (Gd{sub 2}O{sub 3}) nanoparticle is a new contrast agent. It serves to equip the core of each particle with antibodies or ligands. It can freely circulate in blood vessels without amassing in the liver or lungs. This study shows the characteristics of gadolinium oxide nanoparticles to further advance terahertz medical imaging.
- OSTI ID:
- 21301129
- Journal Information:
- AIP Conference Proceedings, Vol. 1119, Issue 1; Conference: 3. IUPAP international conference on women in physics, Seoul (Korea, Republic of), 8-10 Oct 2008; Other Information: DOI: 10.1063/1.3137841; (c) 2009 American Institute of Physics; Country of input: International Atomic Energy Agency (IAEA); ISSN 0094-243X
- Country of Publication:
- United States
- Language:
- English
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