Magnetic Resonance Imaging with laser polarized {sup 129}Xe

Journal Article · Tue Jan 20 00:00:00 EST 1998 · AIP Conference Proceedings

DOI:https://doi.org/10.1063/1.55021· OSTI ID:21182419

Swanson, Scott D; Rosen, Matthew S; Agranoff, Bernard W; Coulter, Kevin P; Welsh, Robert C; Chupp, Timothy E ^[1]

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1. University of Michigan, Ann Arbor, Michigan 48109 (United States)

Magnetic Resonance Imaging with laser-polarized {sup 129}Xe can be utilized to trace blood flow and perfusion in tissue for a variety of biomedical applications. Polarized xenon gas introduced in to the lungs dissolves in the blood and is transported to organs such as the brain where it accumulates in the tissue. Spectroscopic studies combined with imaging have been used to produce brain images of {sup 129}Xe in the rat head. This work establishes that nuclear polarization produced in the gas phases survives transport to the brain where it may be imaged. Increases in polarization and delivered volume of {sup 129}Xe will allow clinical measurements of regional blood flow.

• OSTI ID: 21182419
• Journal Information: AIP Conference Proceedings, Vol. 421, Issue 1; Conference: 7. international workshop on polarized gas targets and polarized beams, Urbana, IL (United States), 18-22 Aug 1997; Other Information: DOI: 10.1063/1.55021; (c) 1998 American Institute of Physics; Country of input: International Atomic Energy Agency (IAEA); ISSN 0094-243X
• Country of Publication: United States
• Language: English

Related Subjects

62 RADIOLOGY AND NUCLEAR MEDICINE
BLOOD
BLOOD FLOW
BRAIN
HEAD
IMAGE PROCESSING
IMAGES
LASER RADIATION
LUNGS
NMR IMAGING
NUCLEAR MAGNETIC RESONANCE
ORIENTED NUCLEI
POLARIZATION
RATS
XENON 129